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PPP3CA

  • Official Full Name

    protein phosphatase 3, catalytic subunit, alpha isozyme

  • Overview

    Calcineurin (CN) is a protein phosphatase also known as protein phosphatase 3, PPP3CA, and calcium-dependent serine-threonine phosphatase, and formerly known as protein phosphatase 2B (PP2B).It activates the T cells of the immune system and can be blo
  • Synonyms

    PPP3CA; protein phosphatase 3, catalytic subunit, alpha isozyme; CALN, CALNA, protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform , protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha); serine/thr;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • CHO
  • E.coli
  • HEK293
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Sf21 Insect Cell
  • Fc
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PPP3CA&PPP3R1-626H Active Recombinant Human PPP3CA&PPP3R1 Sf21 Insect Cell N/A
Human IL13RA2-618HAF488 Active Recombinant Human IL13RA2 Protein, Fc-tagged, Alexa Fluor 488 conjugated CHO Fc
Human IL13RA2-618HAF555 Active Recombinant Human IL13RA2 Protein, Fc-tagged, Alexa Fluor 555 conjugated CHO Fc
Human IL13RA2-618HAF647 Active Recombinant Human IL13RA2 Protein, Fc-tagged, Alexa Fluor 647 conjugated CHO Fc
Human IL13RA2-618HF Active Recombinant Human IL13RA2 Protein, Fc-tagged, FITC conjugated CHO Fc
Human PPP3CA-1922H Recombinant Human PPP3CA, GST-tagged E.coli GST 1-302aa
Human PPP3CA-158H Recombinant Human PPP3CA Mammalian Cell His
Human PPP3CA-26743TH Recombinant Human PPP3CA, His-tagged E.coli His 511 amino acids
Human PPP3CA-951H Recombinant Human PPP3CA, His-tagged E.coli His
Human PPP3CA-7365H Active Recombinant Human PPP3CA protein, His-tagged Insect Cells His Ser2-Gln521
Human PPP3CA-5255H Recombinant Human PPP3CA/PPP3R1 Protein E.coli N/A
Human PPP3CA-001HCL Recombinant Human PPP3CA cell lysate Insect Cell N/A
Human PPP3CA-3897H Recombinant Human PPP3CA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PPP3CA-001H Recombinant Human PPP3CA & PPP3R1 Protein E.coli 1-521 and 1-170
Human PPP3CA-3897H-B Recombinant Human PPP3CA Protein Pre-coupled Magnetic Beads HEK293
Human PPP3CA-5966H Recombinant Human PPP3CA Protein (Ile7-Ser301), N-His tagged E.coli N-His Ile7-Ser301
Rat PPP3CA-4639R Recombinant Rat PPP3CA Protein Mammalian Cell His
Rat PPP3CA-4298R Recombinant Rat PPP3CA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PPP3CA-4298R-B Recombinant Rat PPP3CA Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PPP3CA-3576R Recombinant Rhesus monkey PPP3CA Protein, His-tagged Mammalian Cell His
Rhesus Macaque PPP3CA-3394R Recombinant Rhesus Macaque PPP3CA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PPP3CA-3394R-B Recombinant Rhesus Macaque PPP3CA Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PPP3CA-7831Z Recombinant Zebrafish PPP3CA Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PPP3CA Related Research Area

PPP3CA involved in several pathways and played different roles in them. We selected most pathways PPP3CA participated on our site, such as MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP3CA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayFGF12A;ARR3B;RPS6KAL;TMEM37;FGF22;MINK1;PAK2;IL1B;MAP3K4
Calcium signaling pathwayMLCK2;STIM2;CHRNA7;PRKACB;PRKACAB;ADRB2B;TNNC1;CALML3;TACR3L
cGMP-PKG signaling pathwayVDAC3;GUCY1A3;PPP1CC;MAPK1;PDE5A;GUCY1B3;PLCB4;MEF2D;GNAI1
Oocyte meiosisPPP1R2P9;CALML3;RPS6KA3B;CAMK2D;FBXW11A;YWHABA;FBXW11B;RBX1;CAMK2G
ApoptosisPRKACAB;DIABLOB;CASP2;BIDA;RIPK1L;CAPN1;ADD1;XIAP;DBNLB
Wnt signaling pathwayWNT2B;PRICKLE1;MAPK8;LRP5;WNT5A;FBXW11B;PRKCG;CAMK2B;PLCB1
Axon guidanceKBTBD7;EFNA3B;FES;GDNF;EPHB1;GNAI3;SLIT3;ROBO1;KCNQ3
VEGF signaling pathwaySHC2;AKT2L;PIK3R3;MAPK3;PIK3CG;PPP3R1;PPP3CA;CASP9;MAPK13
Osteoclast differentiationTNF;TGFBR2;CYBA;LILRA3;PIK3R5;IL1R1;MAPK11;SIRP-BETA;IFNGR2
Natural killer cell mediated cytotoxicityIFNA8;IFNB1;BRAF;PIK3CA;KIR2DS5;ULBP1;SAMD3;NCR2;ZAP70
T cell receptor signaling pathwayPIK3CD;CABIN1;NFKBIE;PIK3R5;PIK3R1;MAPK11;ICOS;PPP3CB;CARD11
B cell receptor signaling pathwayBLNK;RAF1;RASGRP3;NFKBIB;ITPR2;RAP2A;PIK3R3;PIK3CG;NFATC1
Long-term potentiationMAPK3;GRIN1;GRIN2A;MAPK1;BRAF;PPP3CA;CALM3;RPS6KA6;PRKACG
Glutamatergic synapseGNAI3;SLC1A7;GNG8;PRKCB;SLC38A1;GRIN2C;SLC1A1;SHANK2;GNB2
Dopaminergic synapseDRD3;PRKACB;ATF6B;PPP2R2A;ITPR3;CALY;AKT2;PRKACA;MAPK12
Oxytocin signaling pathwayPRKACB;NFATC1;GUCY1A3;EEF2K;ACTG1;PPP1R12C;CACNA2D1;OXT;Adcy4
Renin secretionCALM4;PDE1B;PPP3CB;GUCY1A3;PLCB1;NPR1;PRKACB;AQP1;CLCA5
Alzheimers diseaseCOX6A2;APH1B;NAE1;COX7B;ATP5G1;NDUFS2;NDUFA1;CHP;ATP5D
Amyotrophic lateral sclerosis (ALS)CASP12;GRIN2D;PPP3CC;GRIN1;NEFH;BCL2;NOS1;MAP2K3;TOMM40
TuberculosisPPP3R2;AKT2;SPHK1;AKT1;TGFB1;HLA-DQB1;IFNA17;CAP18;TGFB3
HTLV-I infectionDVL1;SMAD4;PIK3R1;CREM;KAT2B;XBP1;ATF4;PRKACG;TGFB3

PPP3CA has several biochemical functions, for example, calcium ion binding, calmodulin binding, calmodulin-dependent protein phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP3CA itself. We selected most functions PPP3CA had, and list some proteins which have the same functions with PPP3CA. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingANKRD5;CIB3;FBLN7;HPCA;PCDHGA1;SULF2;CPNE1;DSG2.1;PVALB1
calmodulin bindingMYH3;ADD3;KCNN1B;SNTA1;UBR4;MYO5B;RGS2;TRPV5;VAMP2
calmodulin-dependent protein phosphatase activityPPP3CB;PPM1F;PPM1A;PPP3CA
drug bindingDRD2;CYP2C9;CHRM3;TOP2A;CHRNB4;CHRNB3;CHRM1;DRD1A;PIGC
enzyme bindingPLSCR4;HIST1H2AL;KAT8;IQCB1;AXIN1;KRT79;KPNB1;ATP6AP2;TARBP2
protein bindingHMGB1;NOX5;POLE4;ZNF16;FAM54B;SKA3;GAK;NGFR;DIEXF
protein dimerization activityMYCH;MESP1;NEUROG2;MEF2AA;POLR2J2;DERL3;OLIG1;TWIST2;DNM1
protein heterodimerization activityPHC2B;ATF6;PDX1;BARD1;BCL2L1;MAP3K7;HIST1H2BE;SUPT3H;TAL1
protein serine/threonine phosphatase activityPP2D1;CDC14AB;PDP1;PPA2;PPEF2;CTDNEP1B;PPM1NB;CDKN3;CDC14A

PPP3CA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP3CA here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP3CA.

PPP3R1; GRB2; C16orf74; Cacng8; USP14; LASP1; Kcnj8; Nfatc1; ABL1

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