Home / Products / ppp2r4


Official Full Name PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
Background Type 2 protein serine/threonine phosphatase (PP2A) is a trimer composed of a catalytic C subunit and two regulatory (A and B) subunits; many isoforms for the A and B subunits have been found. PP2A has a high specific activity against the alpha subunit of phosphorylase kinase and is insensitive to Inhibitor-2. PP2A is distinguishable from PP2B/Calcineurin and PP2C by its partial activity in the absence of divalent cations, and by its high sensitivity to inhibition by okadaic acid. It is also thought to be the principal downmodulator of serine/threonine kinase cascades. PP2B requires Ca2+/calmodulin for activity, and is an activator of NFAT transcription factors. PP2C requires Mg2+, but is insensitive to okadaic acid, microcystin LR, or the calmodulin inhibitor trifluoperazine.
Synonyms PPP2R4; protein phosphatase 2A activator, regulatory subunit 4; protein phosphatase 2A, regulatory subunit B (PR 53); serine/threonine-protein phosphatase 2A activator; phosphotyrosyl phosphatase activator; PP2A phosphatase activator; PR53; PTPA; PP2A subunit B isoform PR53; serine/threonine-protein phosphatase 2A regulatory subunit B; PP2A; MGC2184
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP2R4-27572TH Recombinant Human PPP2R4, His-tagged E.coli His
    Human PPP2R4-2919HCL Recombinant Human PPP2R4 293 Cell Lysate HEK293 N/A
    Human PPP2R4-589H Recombinant Human PPP2R4 E.coli N/A
    Mouse PPP2R4-13260M Recombinant Mouse PPP2R4 Protein Mammalian Cell His
    Chicken PPP2R4-3022C Recombinant Chicken PPP2R4 Mammalian Cell His
    Zebrafish PPP2R4-878Z Recombinant Zebrafish PPP2R4 Mammalian Cell His

    ppp2r4 involved in several pathways and played different roles in them. We selected most pathways ppp2r4 participated on our site, such as Insulin resistance, which may be useful for your reference. Also, other proteins which involved in the same pathway with ppp2r4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Insulin resistance PYGM; RPS6KA3; SREBF1; NFKBIAA; PPARGC1A; GFPT2; PRKAG2; PPP1R3C; RPS6KA2; G6PCA.1

    ppp2r4 has several biochemical functions, for example, ATP binding, contributes_to ATPase activity, peptidyl-prolyl cis-trans isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ppp2r4 itself. We selected most functions ppp2r4 had, and list some proteins which have the same functions with ppp2r4. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding VCP; DNAH11; STRC; SYK; FLT4; ACTG1; NLK1; DGKAA; ATP2B1B; CDK18
    contributes_to ATPase activity ATP5D; MSH2; RFC3; ABCG8; ATP6V1H; ATP5L; ATP5F1; RUVBL2; ATP5J; ATP5H
    peptidyl-prolyl cis-trans isomerase activity FKBP1AB; FKBP10; FKBP4; PPIAB; PPIL3; PPIL2; CWC27; PPIL6; PPIB; RANBP2
    protein binding GPBP1; MIPOL1; OSBPL2; CLC; C16orf79; CP110; RGS3; PPIF; CD300A; ZNF652
    protein heterodimerization activity SYT5; Pdgfa&Pdgfb; CLNS1A; RALGAPA1; ADIPOR2; IL12B; PML; CEBPE; HYPM; ADRB1
    protein homodimerization activity MAPK4; HPS4; PRMT8; RIPK2; NRBP1; GPD1L; STK10; TERT; CTBP1; TBX18
    protein phosphatase 2A binding MASTL; PPP2R2A; PPME1; SMG7; RPS6KB1; AKT1; GRIN3A; PTPN1; MAPT; FOXO1
    protein phosphatase type 2A regulator activity PPP2R5CB; PPP2R5EA; PPP2R1B; PPP2R5A; pab1; PPP2R5E; PPP2R5B; ENSA; PPP2R2B; PPP2R5C
    protein tyrosine phosphatase activator activity PPP2R4; IGFBP3
    receptor binding ANG; GLA; DIAPH1; H2-Q10; Icosl; RSPO1; A2M; NPPC; LTA; CADM3

    ppp2r4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ppp2r4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ppp2r4.

    AMOT; BRINP1; Kiaa1109; TCP1; CCT6A; CCT5; CCT3; CCT8; CCT4; PPP2CA; CCT2; CCT7; AKT1

    Related Services & Products

    Apply For A Coupon

    $50 OFF Your First Purchase

    Apply For a Coupon

    Enter your email here to subscribe.

    creative biomart inc.

    Easy access to products and services you need from our library via powerful searching tools.

    Follow Us

    Copyright © 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy