Ppp2r2a

  • Official Full Name

    protein phosphatase 2, regulatory subunit B, alpha

Recombinant Proteins

  • Mouse
  • Chicken
  • Rat
  • Cynomolgus
  • Human
  • Mammalian Cells
  • HEK293
  • E.coli
  • His
  • Non
  • Avi
  • Fc

    Involved Pathway

    Ppp2r2a involved in several pathways and played different roles in them. We selected most pathways Ppp2r2a participated on our site, such as mRNA surveillance pathway,Sphingolipid signaling pathway,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ppp2r2a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adrenergic signaling in cardiomyocytes CACNA1SB,PPP2R3A,ACTC1,ADRa1A,MYH15,PRKACAA,PRKACA,CACNG2A,ATP1B4,GNAI2A
    mRNA surveillance pathway RBM8A,CPSF2,PPP2R5EA,NXF2,PPP2R2D,ETF1,NCBP1,PABPC4,DAZAP1,GSPT2
    Sphingolipid signaling pathway GNAI2,TNFRSF1A,NFKB1,BID,ABCC1,DEGS1,SPTLC1,RELA,PIK3CG,PPP2R5C
    Tight junction CLDNB,MYLPFA,MYL5,MYH11A,MYH8,CASKA,F11R,PRKCD,MYL7,SHROOM4
    PIK-Akt signaling pathway EPOR,IL2RB,PKN3,GSK3B,PRLR,PPP2CB,IL4,PPP2CA,Ifna15,ITGA8
    Hepatitis C MAPK3,GSK3B,CLDN5,KRAS,RNASEL,IFNA1,TRP53,CLDN4,CLDN3,TP53
    Hippo signaling pathway PARD3,FRMD6,PPP2CB,RASSF1,WNT2,PPP1CA,LLGL2,CRB2,WWTR1,CCND2
    Chagas disease (American trypanosomiasis) FOS,TLR2,PPP2CA,CD3G,C1QB,CXCL8,NFKB1,MYD88,PIK3R3,CASP8
    AMPK signaling pathway HNF4A,PPP2R5A,HMGCR,INS,IGF1,ADIPOR1,LEP,PPP2R3C,GYS2,PRKAA2

    Protein Function

    Ppp2r2a has several biochemical functions, for example, protein binding,protein complex binding,protein phosphatase 2A binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ppp2r2a itself. We selected most functions Ppp2r2a had, and list some proteins which have the same functions with Ppp2r2a. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CCPG1,SPIN1,TCEANC2,ISG15,TAB2,ESR1,CASP14,ERCC4,LBH,FKBP7
    protein phosphatase type 2A regulator activity PPP2R1B,PPP2R1A,ARPP19,ENSA,SET,pab1,ENSAA,PPP2R5EB,EIF2AK2,PPP2R2BB
    protein serine/threonine phosphatase activity PPP3CA,CTDNEP1B,CDC14A,PPM1H,CDC14C,PPM1B,PPP1R3C,EPM2A,PPEF2,PHLPP2
    protein complex binding RPH3A,ULK1,GRIN2A,FBLN1,MYC,NCOA1,ATP6V0D1,CDK2,ANKRD54,Casp3
    protein phosphatase 2A binding ENSA,EIF4EBP1,STRN,TP53,SMG7,SMG5,ENSAA,BCL2,ANKLE2,AKT1
    tau protein binding FKBP4,HDAC6,BIN1,SERPINB1A,AATF,SNCA,S100B,DYRK1A,APOE

    Interacting Protein

    Ppp2r2a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ppp2r2a here. Most of them are supplied by our site. Hope this information will be useful for your research of Ppp2r2a.

    PPP2R1A;PPP2CA;PPP2CB;PPP2R1B

    Resources

    References

    • Kurimchak, A; Grana, X; et al. PP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues. CELL CYCLE 14:18-30(2015).
    • Zhang, DB; Wang, J; et al. miR-136 Modulates TGF-beta 1-Induced Proliferation Arrest by Targeting PPP2R2A in Keratinocytes. Biomed Research International :-(2015).

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