PPP1R14A
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Official Full Name
protein phosphatase 1, regulatory (inhibitor) subunit 14A
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Overview
The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. -
Synonyms
PPP1R14A; protein phosphatase 1, regulatory (inhibitor) subunit 14A; PPP1INL; protein phosphatase 1 regulatory subunit 14A; 17 kDa PKC potentiated inhibitory protein of PP1; 17 KDa protein; CPI 17; PKC potentiated inhibitory protein of PP1; 17-KDa protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- C
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
PPP1R14A involved in several pathways and played different roles in them. We selected most pathways PPP1R14A participated on our site, such as Vascular smooth muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1R14A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Vascular smooth muscle contraction | ARHGEF11;CALM3;PLA2G4F;CALM1;PLA2G2E;RHOAB;CACNA1C;KCNMB4;CACNA1SB |
PPP1R14A has several biochemical functions, for example, protein phosphatase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1R14A itself. We selected most functions PPP1R14A had, and list some proteins which have the same functions with PPP1R14A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein phosphatase inhibitor activity | PPP1R14B;PPP1R36;PPP1R26;PPP1R14A;PPP1R2P3;GLC8;ENSA;PHACTR3;PPP1R10 |
PPP1R14A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1R14A here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1R14A.
CSNK1A1; PRNP
- Q&As
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