ppp1cc
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  • Official Full Name
  • protein phosphatase 1, catalytic subunit, gamma isozyme
  • Background
  • Protein phosphatase 1, gamma 1 (PP-1G) is a member of the PPP phosphatase family. Type 1 protein Ser/Thr phosphatases (PP1) have a high specific activity against phosphorylase, and are resistant to okadaic acid up to concentrations of 50 nM, but sensitive to Inhibitor-2 and microcystin LR.
  • Synonyms
  • PPP1CC; protein phosphatase 1, catalytic subunit, gamma isozyme; protein phosphatase 1, catalytic subunit, gamma isoform; serine/threonine-protein phosphatase PP1-gamma catalytic subunit; PP1gamma; serine/threonine phosphatase 1 gamma; protein phosphatase 1C catalytic subunit; PP-1G; PPP1G
Cat.#:PPP1CC-2401HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Phosphatase 1, Catalytic Subunit, Gamma Isozyme, His-tagged
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Cat.#:PPP1CC-29101THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PPP1CC
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Cat.#:PPP1CC-648HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP1CC Protein, His-tagged
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Cat.#:PPP1CC-844HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP1CC, His-tagged
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Cat.#:PPP1CC-13211MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PPP1CC Protein
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Cat.#:PPP1CC-3559RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PPP1CC Protein, His-tagged
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Cat.#:PPP1CC-1339CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PPP1CC
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Cat.#:PPP1CC-2948HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PPP1CC 293 Cell Lysate
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Involved Pathway

PPP1CC involved in several pathways and played different roles in them. We selected most pathways PPP1CC participated on our site, such as mRNA surveillance pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1CC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
mRNA surveillance pathway
PNN; FIP1L1; PAPOLG; NCBP2; SRRM1; MAGOHB; PPP2R5E; BAT1; PABPN1; SMG5
cGMP-PKG signaling pathway
PLCB2; AKT1; GNAI3; SRF; PPP1CB; OPRD1; PRKG1; CREB3L2; INS; MAPK3
cAMP signaling pathway
NFKBIA; ACOX1; PIK3CG; FXYD1; CREB3L2; MAPK1; RHOA; LIPE; RAC1; CREB3L3
Oocyte meiosis
YWHAE; RPS6KA3B; IGF1; CUL1B; CALM3; PPP3CCB; PPP2R1B; ANAPC2; FBXO5; CCNB1
Adrenergic signaling in cardiomyocytes
ADRB3A; GNAI2B; CACNG7A; CACNA2D4; MYH15; MYH7; CAMK2G; ATP1B2; AKT3A; RAPGEF3
Vascular smooth muscle contraction
CALM3A; PPP1R14AB; CALCRLA; PRKCDA; ARHGEF11; GNA13A; CALM2; PLCB3; PLA2G12B; GNA12A
Hippo signaling pathway
CTNNA3; PARD6A; YWHAH; WNT9B; TEAD3; BMP4; BTRC; WNT4; PPP1CC; SOX2
Focal adhesion
AKT2; FYNB; ITGB3; COL5A1; LAMC3; VASP; BRAF; PAK3; CCND2A; PRKCBB
Platelet activation
PTGS1; PRKCI; ITGB1; ITPR1; PIK3CG; MYLK4; PRKACG; ITPR3; PLCB3; GNAI2
Long-term potentiation
PLCB4; MAP2K2; PRKACA; EP300; CALM3; PPP1CA; CAMK2D; KRAS; GRM1; GRIA1
Dopaminergic synapse
PPP2R2B; SLC18A2; GSK3A; PPP2R5B; CALM1; SCN1A; CALM3; PPP2R2C; DRD1A; CAMK2B
Inflammatory mediator regulation of TRP channels
NGF; PTGER4; CALML5; ACCN3; IL1B; CYP2C37; PIK3CD; CYP2C38; TRPV2; PTGER2
Regulation of actin cytoskeleton
PDGFRB; PIKFYVE; MLCK2; ITGAM; SLC9A1; PIP5K1AA; FGF6B; PIK3R2; PAK2B; VAV3
Insulin signaling pathway
GSK3AA; GYS2; BRAF; HK3; INS1; RHEB; CALML5; PPP1R3A; RPS6KB2; PRKACAB
Oxytocin signaling pathway
PIK3R1; PLCB3; MYL6B; MYL6; KRAS; PRKAA2; NFATC2; CACNA2D3; PLA2G4C; NFATC1
Insulin resistance
IKBKB; PYGMA; PRKAG2; RPS6KA3; NFKBIA; G6PC; SOCS3; TNFRSF1A; CD36; PRKCBB
Amphetamine addiction
ATF4; GRIN2C; CREB3; PPP1CC; GRIN2A; GRIN3B; PPP3CC; PDYN; GRIN1; HDAC1
Alcoholism
CAMKK1; HIST1H2BJ; HIST1H2AB; GNG12; HIST1H2BM; HIST1H4G; HIST1H4F; GM14482; FOSB; HIST2H2AC
Herpes simplex infection
FAS; TAB2; IFNPHI3; IFNAR1; HLA-DRA; TBK1; IKBKE; TNFRSF1A; HLA-DPA1; H2-Q10
Proteoglycans in cancer
RRAS2; WNT2B; GRB2; RRAS; PTPN6; WNT5A; FGFR1; PIK3R1; CD44; MET

Protein Function

PPP1CC has several biochemical functions, for example, metal ion binding, phosphatase activity, phosphoprotein phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1CC itself. We selected most functions PPP1CC had, and list some proteins which have the same functions with PPP1CC. You can find most of the proteins on our site.
Function
Related Protein
Function metal ion binding
Related Protein ZNF625; PPARG; BTR16; PEG3; POLR3A; GNA11; LYAR; ZNF580; ZNF652; ZNF428
Function phosphatase activity
Related Protein CDC14AA; MTMR7A; PTPRJA; PTPN23A; CDC14A; PHOSPHO2; MINPP1B; ACPP; DUSP22B; PTENA
Function phosphoprotein phosphatase activity
Related Protein PTPN20; PPM1BA; PTPN2A; PTEN; PHLPP1; PTPRU; SSH2; TIMM50; PPM1LA; DUSP10
Function poly(A) RNA binding
Related Protein SF3B2; HNRNPM; RPL35A; DDX18; FKBP3; RPP25; SLC25A5; TMSB4X; NXF2; C11orf68
Function protein N-terminus binding
Related Protein ZWINT; PHB2; MYO7A; CSNK2A2; TRP53; LACRT; KCNIP1; SYNGR3; PIAS3; MEN1
Function protein binding
Related Protein IKZF1; G6PD; ACE; MRPL9; C18orf1; RABIF; SMARCB1; TUBG1; TEX11; IL13
Function protein kinase binding
Related Protein HSPB1; KIF13B; RHOD; PPP1CB; MVP; LIMS1; TEX14; PIH1D1; CAV2; CALM
Function protein serine/threonine phosphatase activity
Related Protein PPP2R5D; PPP3CA; PPP1CC; PPM1LA; PPM1A; PPM1G; PPM1H; LCK; PPP1R15B; CTDNEP1A

Interacting Protein

PPP1CC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1CC here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1CC.
TP53BP2; PPP1R2; ZFYVE9; URI1