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Official Full Name protein phosphatase 2, catalytic subunit, beta isozyme
Background This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit.
Synonyms PPP2CB; protein phosphatase 2, catalytic subunit, beta isozyme; protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; PP2Abeta; protein phosphatase 2A catalytic subunit; beta isoform; PP2A beta; PP2A-beta; PP2AB_HUMAN; PP2CB; Protein phosphatase 2 catalytic subunit beta isozyme; Protein phosphatase 2, catalytic subunit, beta isoform; Protein phosphatase 2A catalytic subunit beta isoform; Protein phosphatase type 2A catalytic subunit; Serine/threonine protein phosphatase 2A catalytic subunit beta; OTTHUMP00000225455; protein phosphatase 2A catalytic subunit, beta isoform; serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP2CB-1178H Recombinant Human PPP2CB Protein (1-309 aa), GST-tagged E.coli GST
    Human PPP2CB-27931TH Recombinant Human PPP2CB Wheat Germ N/A
    Human PPP2CB-2927HCL Recombinant Human PPP2CB 293 Cell Lysate HEK293 N/A
    Human PPP2CB-2928HCL Recombinant Human PPP2CB 293 Cell Lysate HEK293 N/A
    Human PPP2CB-650H Recombinant Human PPP2CB Protein, His-tagged E.coli His
    Mouse PPP2CB-13250M Recombinant Mouse PPP2CB Protein Mammalian Cell His
    Rat PPP2CB-4632R Recombinant Rat PPP2CB Protein Mammalian Cell His
    Rhesus Macaque PPP2CB-3570R Recombinant Rhesus monkey PPP2CB Protein, His-tagged Mammalian Cell His
    Chicken PPP2CB-6681C Recombinant Chicken PPP2CB Mammalian Cell His
    Zebrafish PPP2CB-12481Z Recombinant Zebrafish PPP2CB Mammalian Cell His

    ppp2cb involved in several pathways and played different roles in them. We selected most pathways ppp2cb participated on our site, such as mRNA surveillance pathway, Sphingolipid signaling pathway, Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ppp2cb were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    mRNA surveillance pathway PABPC1L2A; BAT1; UPF1; GSPT1; GSPT1L; PABPN1; PAPOLG; MSI2B; NXF3; PABPC1
    Sphingolipid signaling pathway AKT1; S1PR4; GAB2; MAPK11; PPP2R3A; DEGS2; MAPK10; MAP2K2; PLD1; GNA12
    Oocyte meiosis SMC1A; FBXO43; PPP2R5C; ANAPC7; BUB1; CCNB2; Ar; CALM1B; CPEB1; INS
    PIK-Akt signaling pathway PGF; IFNA7; FASLG; IL6; CCNE2; NGF; COL4A1; EPO; INS; BCL2
    AMPK signaling pathway SLC2A4; CCNA2; STK11; IRS4; CREB1; ADIPOR2; G6PC; PFKFB2; PPARG; PFKFB4
    Adrenergic signaling in cardiomyocytes CACNA2D1; GNAI3; CALM2B; PRKACAA; ATF4B1; MAPK1; ATF6B; CALM1B; SCN1BB; PPP2R5B
    TGF-beta signaling pathway ID3; SKP1; SMAD4; TGFBR1; SMAD7B; LFT2; CUL1B; ACVR1C; TGFBR1B; ACVR2A
    Hippo signaling pathway TEAD3; YWHAZ; RASSF1; SMAD4; FZD1; WNT8B; PPP2R1A; TGFB3; ACTG1; WNT6
    Dopaminergic synapse GNG7; GNAS; GNG10; GNG4; ARNTL; DRD3; PPP3CA; PPP2R1B; CALML5; CALM2
    Long-term depression GNAI1; PLA2G4C; PRKG1; LYN; GRIA2; NRAS; PLA2G4A; PRKG2; PLCB4; GRIA1
    Chagas disease (American trypanosomiasis) SMAD2; PIK3CG; IRAK1; C1QA; TGFB3; PPP2R1A; TICAM1; FAS; IFNGR1; FADD
    Hepatitis C CLDN6; LDLR; MAPK11; Ifna11; IFNA8; CLDN9; TRAF6; OAS1; GRB2; OSTN

    ppp2cb has several biochemical functions, for example, metal ion binding, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ppp2cb itself. We selected most functions ppp2cb had, and list some proteins which have the same functions with ppp2cb. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding MGAT4C; TRIM35-21; B4GALT2; ZNF581; ZFP292; MLL5; NOS2B; FTH1A; NRXN2B; ZNF223
    protein C-terminus binding TOP2A; ERCC6; MED12; NEFL; KPNA3; TFCP2; TERF2; RBFOX1; CDC20; PEX1
    protein binding SP100; ACAA1; PPP3R1; ZNF567; TDG; NPC2; ABT1; LILRB4; FRMD4B; ATXN3
    contributes_to protein serine/threonine phosphatase activity PPP2CB; CYCS

    ppp2cb has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ppp2cb here. Most of them are supplied by our site. Hope this information will be useful for your research of ppp2cb.


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