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Official Full Name protein phosphatase 3, catalytic subunit, gamma isozyme
Background Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene.
Synonyms PPP3CC; protein phosphatase 3, catalytic subunit, gamma isozyme; protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform , protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma); serine/threonine-protein
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP3CC-2913HCL Recombinant Human PPP3CC 293 Cell Lysate HEK293 N/A
    Human PPP3CC-5693H Recombinant Human PPP3CC Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human PPP3CC-736H Recombinant Human PPP3CC Protein (2-512 aa), His-tagged E.coli His
    Mouse PPP3CC-13268M Recombinant Mouse PPP3CC Protein Mammalian Cell His
    Mouse Ppp3cc-5082M Recombinant Mouse Ppp3cc Protein, Myc/DDK-tagged HEK293T Myc/DDK

    ppp3cc involved in several pathways and played different roles in them. We selected most pathways ppp3cc participated on our site, such as MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ppp3cc were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway FGF19; NTF4; CACNA2D3; ECSIT; DDIT3; CDC42; PPP3CCA; TAB2; MKNK2; MAPK8IP3
    Calcium signaling pathway CACNA1BA; ADORA2AA; PRKACBB; DRD5; HTR7; PLCD3A; P2RX8; EDNRB; RYR2; ATP2A2
    cGMP-PKG signaling pathway FXYD2; MEF2D; PIK3R2; MAP2K1; PIK3CG; PIK3R1; GUCY1B3; NOS3; CREB3L2; AKT1
    Oocyte meiosis RBX1; PPP2R5D; INS2; Ar; CUL1B; INS1; PPP1CAA; MAPK12B; PRKACG; CAMK2G
    Apoptosis PIK3R1; FADD; IRAK1; HIST1H1B; IL1R1; XIAP; CTNNB1; E2F1; BIRC8; PLECA
    Wnt signaling pathway PRICKLE1; FZD5; RAC3; TBL1XR1; PORCNL; CUL1B; SMAD4; PPP3R1; PLCB1; PLCB3
    Axon guidance CFL2; ANK2B; SEMA3AB; UNC5A; EFNB3; SPTBN2; DLG3; MAPK3; CLASP1; RHOGA
    VEGF signaling pathway HRASB; RAC3B; PPP3CB; MAP2K2A; HSPB1; PLA2G4C; RAC1B; PXN; SHC2; MAP2K1
    Osteoclast differentiation IKBKB; NOX1; LILRA4; CAMK4; IFNAR1; FCGR2A; CALCR; FCGR2C; FOSL2; AKT1
    Natural killer cell mediated cytotoxicity RAET1D; KLRC2; TNFRSF10D; RAC1; ITGB2L; FCER1G; TNFRSF10C; PIK3R5; PRKCA; KRAS
    T cell receptor signaling pathway CBL; IKBKB; CBLB; TEC; MAPK11; PIK3CB; PLCG1; AKT1; ZAP70; PAK3
    B cell receptor signaling pathway SYK; INPPL1; CD22; CR2; LIME1; CARD11; BCL10; CSK; PPP3R2; LAT2
    Long-term potentiation CAMK2A; NRAS; PPP1CC; PRKACA; CALML3; PRKCG; GRIA2; CALM3; GRIN1; RAP1A
    Glutamatergic synapse GNB2; GNAS; SLC38A2; SLC17A7; GRIK2; SHANK3; SLC17A6; HOMER1; GRIK5; GNG5
    Dopaminergic synapse KIF5A; TH; GNB4; GNG5; ATF6B; GNB1; GNG12; PRKACG; PPP1CA; CAMK2G
    Oxytocin signaling pathway PPP3CC; GNAI1; ITPR3; PRKAB2; ROCK2; MYL9; TRPM2; PPP3R1; PRKAA2; PLCB4
    Renin secretion GNAQ; REN2; ITPR1; PRKG2; CLCA5; PTGER4; CALM3; PDE1A; PPP3CC; GUCY1A3
    Alzheimers disease NAE1; CALML5; NDUFV1; BID; MT-ATP6; mt-Atp8; ERN1; CASP7; NDUFS2; CAPN1
    Amyotrophic lateral sclerosis (ALS) MAPK13; BAD; GRIA2; TNF; CASP9; MAPK12; GRIN2B; PPP3R2; BAX; CYCS
    Tuberculosis IFNA14; FADD; CD209B; LSP1; LBP; Cd209g; SPHK2; TLR4; Ifna15; IL23

    ppp3cc has several biochemical functions, for example, calmodulin binding, metal ion binding, phosphoprotein phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ppp3cc itself. We selected most functions ppp3cc had, and list some proteins which have the same functions with ppp3cc. You can find most of the proteins on our site.

    Function Related Protein
    calmodulin binding ADD2; PHKA2; CAMKV; EEA1; KCNN1; SNTA1; MYH3; MIP; MTAP6; RGS4
    metal ion binding ACLY; ZNF766; RNF216; LNPA; ARHGEF38; ZKSCAN17; HRG; ZNF485; PARN; HIVEP2A
    phosphoprotein phosphatase activity ACP2; PPM1H; PTPRJA; PPP3CCB; PPP4CA; PTPN11B; PTPN4A; PTPREB; PPM1NB; PTPRQ
    protein binding MED24; ICAM5; SYNJ2BP; MAP2K6; FCER1G; TNNI3; SOX1; ZNF124; C12orf49; TSSK6

    ppp3cc has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ppp3cc here. Most of them are supplied by our site. Hope this information will be useful for your research of ppp3cc.

    AMPH; CSNK2B; HAX1; SDC2; ybfM; yaaO; ITPKC; THAP7

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