| Description : |
This gene encodes a member of the cadherin protein family. Cadherins are a family of calcium-dependent adhesion molecules that mediate cell-cell adhesion in all solid tissues and modulate a wide variety of processes, including cell polarization, migration and differentiation. Cadherin domains occur as repeats in the extracellular region and are thought to contribute to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. This protein is expressed in gastrointestinal epithelial cells and may be upregulated during allergic inflammation. This protein interacts with alpha integrins and may also be involved in leukocyte migration and adhesion. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
92.2 kDa |
| AA Sequence : |
MAMRSGRHPSLLLLLVLLLWLLQVS IIDSVQQETDDLTKQTKEKIYQPLR RSKRRWVITTLELEEEDPGPFPKLI GELFNNMSYNMSLMYLISGPGVDEY PEIGLFSLEDHENGRIYVHRPVDRE MTPSFTVYFDVVERSTGKIVDTSLI FNIRISDVNDHAPQFPEKEFNITVQ ENQSAGQPIFQMLAVDLDEENTPNS QVLYFLISQTPLLKESGFRVDRLSG EIRLSGCLDYETAPQFTLLIRARDC GEPSLSSTTTVHVDVQEGNNHRPAF TQENYKVQIPEGRASQGVLRLLVQD RDSPFTSAWRAKFNILHGNEEGHFD ISTDPETNEGILNVIKPLDYETRPA QSLIIVVENEERLVFCERGKLQPPR KAAASATVSVQVTDANDPPAFHPQS FIVNKEEGARPGTLLGTFNAMDPDS QIRYELVHDPANWVSVDKNSGVVIT VEPIDRESPHVNNSFYVIIIHAVDD GFPPQTATGTLMLFLSDINDNVPTL RPRSRYMEVCESAVHEPLHIEAEDP DLEPFSDPFTFELDNTWGNAEDTWK LGRNWGQSVELLTLRSLPRGNYLVP LFIGDKQGLSQKQTVHVRICPCASG LTCVELADAEVGLHVGALFPVCAAF VALAVALLFLLRCYFVLEPKRHGCS VSNDEGHQTLVMYNAESKGTSAQTW SDVEGQRPALLICTAAAGPTQGVKD LEEVPPSAASQSAQARCALGSWGYG KPFEPRSVKNIHSTPAYPDATMHRQ LLAPVEGRMAETLNQKLHVANVLED DPGYLPHVYSEEGECGGAPSLSSLA SLEQELQPDLLDSLGSKATPFEEIY SESGVPSTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
