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Official Full Name cadherin-related 23
Background This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Alternative splice variants encoding different isoforms have been described.
Synonyms CDH23; cadherin-related 23; cadherin related 23 , cadherin like 23 , DFNB12, USH1D; cadherin-23; cadherin related family member 23; CDHR23; Age related hearing loss 1; Ahl 1; Ahl; Ahl1; Bob; Bobby; Bus; Bustling; Cadherin 23; Cadherin23; CDH 23; Mdfw; Modifier of deaf waddler; nmf112; nmf181; nmf252; Otocadherin; USH 1D; USH1 D; USH1D; Waltzer; cadherin-like 23; OTTHUMP00000020837; OTTHUMP00000020838; cadherin-related family member 23
    • Species :
    • Human
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDH23-0986H Recombinant Human CDH23 Protein Wheat Germ N/A
    Human CDH23-0987H Recombinant Human CDH23 Protein, GST-Tagged Wheat Germ GST
    Human CDH23-11038H Recombinant Human CDH23, GST-tagged E.coli GST
    Human CDH23-429H Recombinant Human CDH23 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Human CDH23-471H Recombinant Human CDH23 Protein, His-tagged E.coli His
    Rat CDH23-1293R Recombinant Rat CDH23 Protein Mammalian Cell His
    Zebrafish CDH23-12819Z Recombinant Zebrafish CDH23 Mammalian Cell His

    cdh23 involved in several pathways and played different roles in them. We selected most pathways cdh23 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with cdh23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    cdh23 has several biochemical functions, for example, calcium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cdh23 itself. We selected most functions cdh23 had, and list some proteins which have the same functions with cdh23. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding PROZ; PITPNM2; CABP4; MYL6; STIM1; OTOFA; ANXA2; SLIT1; CAPN3B; SPTA1
    protein binding BCL2; STX12; MMP2; RRM2; CD244; GATA6; ESYT1; CAPN1; DCPS; NRXN1

    cdh23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdh23 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdh23.


    Tang, PC; Watson, GM; et al. Cadherin-23 May Be Dynamic in Hair Bundles of the Model Sea Anemone Nematostella vectensis. PLOS ONE 9:-(2014).
    Lagziel, A; Overlack, N; et al. Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D. MOLECULAR VISION 15:1843-1857(2009).

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