CDH15

  • Official Full Name

    Cadherin 15, Type 1, M-cadherin (Myotubule)

  • Overview

    This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation.
  • Synonyms

    cadherin 15, type 1, M-cadherin (myotubule); CDH3; cadherin-15; cadherin-3; cadherin-14; CDHM; MCAD; MRD3; CDH14; CDH15; muscle-cadherin; OTTHUMP00000175347; M-cadherin; Muscle cadherin;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • Mammalian Cell
  • Fc
  • His
  • Avi
  • T7
  • Non
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CDH15-50H Recombinant Human CDH15 protein, T7/His-tagged E.coli His&T7 61-246
Human CDH15-0805H Recombinant Human CDH15 Protein (Leu61-Phe260), N-His tagged E.coli His Leu61-Phe260
Mouse Cdh15-2093M Recombinant Mouse Cdh15 protein, His & T7-tagged E.coli His&T7 Leu60~Phe374
Mouse CDH15-3167M Recombinant Mouse CDH15 Protein Mammalian Cell His
Mouse CDH15-1506M Recombinant Mouse CDH15 Protein, His (Fc)-Avi-tagged HEK293 His&Fc&Avi
Mouse CDH15-1506M-B Recombinant Mouse CDH15 Protein Pre-coupled Magnetic Beads HEK293
Rat Cdh15-7476R Recombinant Rat Cdh15, Fc tagged Human Cell Fc Met1-Gly602
Rat CDH15-1484RCL Recombinant Rat CDH15 cell lysate Human Cell Non
Homo sapiens (Human) RFL31388HF Recombinant Full Length Human Cadherin-15(Cdh15) Protein, His-Tagged E.coli expression system His Full Length (61-814)
Mus musculus (Mouse) RFL28981MF Recombinant Full Length Mouse Cadherin-15(Cdh15) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (60-784)
Zebrafish CDH15-11885Z Recombinant Zebrafish CDH15 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CDH15 involved in several pathways and played different roles in them. We selected most pathways CDH15 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)ESAM;CLDN8;HLA-DPB1;HLA-DRB1;NADL1.2;GLG1;NRXN3A;HLA-DRB4;CLDNE

CDH15 has several biochemical functions, for example, calcium ion binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH15 itself. We selected most functions CDH15 had, and list some proteins which have the same functions with CDH15. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingMYL9A;EFHB;PCDHA2;ADAM8;PLCD1;PROS1;CRNN;PCDH12;KIAA0494
metal ion bindingZNF445;HRG;ZNF652;ZNF565;ATP5S;TDO2B;ZFP287;ZFP382;TNKS2
protein bindingDGKZ;CBX8;RTN4A;PKD1L3;PROX1;MLLT4;SLMAP;AP5Z1;MYH10

CDH15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDH15 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDH15.

Research Area

Related articles

Storer, NY; White, RM; et al. Zebrafish rhabdomyosarcoma reflects the developmental stage of oncogene expression during myogenesis. DEVELOPMENT 140:3040-3050(2013).
Bartnik, M; Szczepanik, E; et al. Application of array comparative genomic hybridization in 102 patients with epilepsy and additional neurodevelopmental disorders. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 159B:760-771(2012).
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