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Official Full Name cadherin 3, type 1, P-cadherin (placental)
Background This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Synonyms CDH3; cadherin 3, type 1, P-cadherin (placental); CDHP; HJMD; PCAD
    • Species :
    • Human
    • Mouse
    • Pig
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • Fc
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDH3-0989H Recombinant Human CDH3 Protein, GST-Tagged Wheat Germ GST
    Human Cdh3-1673M Recombinant Mouse Cdh3 protein, Fc-tagged HEK293 N/A
    Human CDH3-168H Recombinant Human CDH3, His-tagged HEK293 His
    Human CDH3-281H Recombinant Human CDH3, T7/His-tagged E.coli T7/His
    Human CDH3-289H Recombinant Human CDH3, MYC/DDK-tagged HEK293 Myc/DDK
    Human CDH3-488H Recombinant Human CDH3 protein, His/Fc-tagged NS0 His/Fc
    Human CDH3-5724H Recombinant Human CDH3 protein, His-tagged E.coli His
    Human CDH3-5818H Recombinant Human CDH3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CDH3-7636HCL Recombinant Human CDH3 293 Cell Lysate HEK293 N/A
    Mouse CDH3-3177M Recombinant Mouse CDH3 Protein Mammalian Cell His
    Mouse Cdh3-5725M Recombinant Mouse Cdh3 protein, His-tagged E.coli His
    Mouse Cdh3-5726M Recombinant Mouse Cdh3 protein, His & GST-tagged E.coli His/GST
    Mouse Cdh3-862M Recombinant Mouse Cdh3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Pig CDH3-2232P Recombinant Pig CDH3 Protein (1-145 aa), His-tagged Yeast His

    cdh3 involved in several pathways and played different roles in them. We selected most pathways cdh3 participated on our site, such as Adherens junctions interactions, Cell adhesion molecules (CAMs), Cell junction organization, which may be useful for your reference. Also, other proteins which involved in the same pathway with cdh3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adherens junctions interactions CDH10A; CDH12A; CDH13; CDH8; CADM2; CADM2A; JUP; CDH5; CTNNA1; CTNND1
    Cell adhesion molecules (CAMs) CNTNAP2A; ITGA6; Ntng2; ALCAMA; GLG1; CDH4; CLDN11B; JAM3; NLGN4X; CD8B1
    Cell junction organization CDH12; CLDN7; CDH10A; INADL; PLEC; TESK1; FBLIM1; ANG; CDH7; PLECA
    Cell-Cell communication RSU1; INADL; SKAP2; F11R.2; KIRREL3; SIRPB1; JUPA; PARVB; FBLIM1; CLDN4
    Cell-cell junction organization CDH12; ANG; CDH8; CDH3; CLDN20; CDH9; CTNND1; CLDN4; CDH18A; CDH24

    cdh3 has several biochemical functions, for example, calcium ion binding, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by cdh3 itself. We selected most functions cdh3 had, and list some proteins which have the same functions with cdh3. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding PROS1; MYL5; KCNIP4; MCTP2; ANXA1C; HPCAL4; OTOFA; CLSTN1; PCDH2G6; SPTAN1
    molecular_function UBALD1B; CDKAL1; SPON2A; SMGC; GM8677; CD82A; CCDC169; MTMR12; RMI2; ARHGEF39

    cdh3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdh3 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdh3.

    IGF1R; q7ard3_yerpe; y551_bacan; YAP1; AP2M1

    Watson, S; Sarris, M; et al. Limbal Dermoid Epithelium Shares Phenotypic Characteristics Common to Both Hair Epidermal and Limbal Epithelial Stem Cells. CURRENT EYE RESEARCH 38:835-842(2013).
    Yoshioka, H; Yamamoto, S; et al. In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy. CANCER IMMUNOLOGY IMMUNOTHERAPY 61:1211-1220(2012).

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