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CDH6

  • Official Full Name

    cadherin 6, type 2, K-cadherin (fetal kidney)

  • Overview

    This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.
  • Synonyms

    CDH6; cadherin 6, type 2, K-cadherin (fetal kidney); cadherin-6; K Cadherin; CAD6; KCAD; FLJ14176; DKFZp564N1116;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus
  • Cynomolgus / Rhesus macaque
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Fc
  • GST
  • HIS
  • His (Fc)
  • Avi
  • N/A
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CDH6-071H Recombinant Human CDH6 Protein, Fc-tagged HEK293 Fc
Human CDH6-110H Recombinant Human CDH6 protein, T7/His-tagged E.coli T7/His
Human CDH6-668H Recombinant Human CDH6 protein, His-tagged HEK293 His Thr19-Ala615
Human CDH6-070H Recombinant Human CDH6 Protein, HIS-tagged HEK293 HIS
Human CDH6-0992H Recombinant Human CDH6 Protein, GST-Tagged Wheat Germ GST
Human CDH6-2727HCL Recombinant Human CDH6 cell lysate Human Cell N/A
Human CDH6-1255H Active Recombinant Human CDH6 protein, His-tagged HEK293 His Thr 19 - Ala 615
Human CDH6-3691H Recombinant Human CDH6 protein, GST-tagged E.coli GST 619 - 665 aa
Human CDH6-2184H Active Recombinant Human CDH6 protein, Fc-tagged HEK293 Fc Thr19-Ala615
Human CDH6-0201H Recombinant Human CDH6 Protein (Thr22-Ala615), C-His-tagged Mammalian cells C-His Thr22-Ala615
Human CDH6-3150HF Recombinant Full Length Human CDH6 Protein, GST-tagged In Vitro Cell Free System GST 663 amino acids
Human CDH6-111H Recombinant Human CDH6 Protein, His-tagged HEK293 His 790
Mouse Cdh6-593M Active Recombinant Mouse Cdh6 Protein, His-tagged Mammalian cells His Met1-Ala615
Mouse Cdh6-7411M Recombinant Mouse Cdh6 protein(Met1-Ala615), His-tagged HEK293 C-His Met1-Ala615
Mouse CDH6-1478MCL Recombinant Mouse CDH6 cell lysate Human Cell N/A
Mouse Cdh6-1510M-B Recombinant Mouse Cdh6 Protein Pre-coupled Magnetic Beads HEK293
Mouse CDH6-2185M Active Recombinant Mouse CDH6 protein, His-tagged HEK293 His Thr19-Ala615
Mouse Cdh6-1510M Recombinant Mouse Cdh6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CDH6-1098R Recombinant Rat CDH6 Protein, His-tagged HEK293 His
Rat CDH6-1294R Recombinant Rat CDH6 Protein Mammalian Cell His
Rat CDH6-952R-B Recombinant Rat CDH6 Protein Pre-coupled Magnetic Beads HEK293
Rat CDH6-952R Recombinant Rat CDH6 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus CDH6-1102C Recombinant Cynomolgus CDH6 Protein (Met1-Gly614), His-tagged HEK293 His Met1-Gly614
Cynomolgus / Rhesus macaque CDH6-2171C Active Recombinant Cynomolgus / Rhesus macaque CDH6 protein, His-tagged HEK293 His Thr22-Gly614
Homo sapiens (Human) RFL11939HF Recombinant Full Length Human Cadherin-6(Cdh6) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (54-790)
Mus musculus (Mouse) RFL23555MF Recombinant Full Length Mouse Cadherin-6(Cdh6) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (54-790)
Rattus norvegicus (Rat) RFL36572RF Recombinant Full Length Rat Cadherin-6(Cdh6) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (54-789)
Zebrafish CDH6-2187Z Recombinant Zebrafish CDH6 Mammalian Cell His
Chicken CDH6-1154C Recombinant Chicken CDH6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CDH6 Related Articles
  • CDH6 Related Research Area

CDH6 involved in several pathways and played different roles in them. We selected most pathways CDH6 participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adherens junctions interactionsANG;CDH9;CADM2;CDH18;CDH24;CDH6;CDH4;CDH18A;CADM2B
Cell junction organizationCLDN4;ITGB1B.1;CDH12A;COL17A1A;CLDN3;INADL;CDH10A;CDH3;LIMS1
Cell-Cell communicationKIRREL3;CDH11;CDH13;KIRREL3L;PVRL2L;CDH10;CDH24;CDH18;TESK1
Cell-cell junction organizationJUPA;CDH6;CDH3;CDH10A;JUP;CDH18A;CTNND1;CDH13;CDH24
Neural Crest DifferentiationDLX5;ASCL1;DCT;TFAP2B;FOXD3;OLIG2;HEY2;MBP;CTBP2

CDH6 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH6 itself. We selected most functions CDH6 had, and list some proteins which have the same functions with CDH6. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingDLB;ACTN3B;CDH6;PCDH2AB3;PCDH1G26;MYLZ3;NOTCH4;SWAP70;OCM2

CDH6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDH6 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDH6.

Butler, MG; Rafi, SK; et al. Whole Exome Sequencing in Females with Autism Implicates Novel and Candidate Genes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 16:1312-1335(2015).
Clay, MR; Halloran, MC; et al. Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition. DEVELOPMENT 141:2506-2515(2014).
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