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Official Full Name cadherin 6, type 2, K-cadherin (fetal kidney)
Background This gene encodes a member of the cadherin superfamily. Cadherins are membrane glycoproteins that mediate homophilic cell-cell adhesion and play critical roles in cell differentiation and morphogenesis. The encoded protein is a type II cadherin and may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.
Synonyms CDH6; cadherin 6, type 2, K-cadherin (fetal kidney); cadherin-6; K Cadherin; CAD6; KCAD; FLJ14176; DKFZp564N1116
    • Species :
    • Chicken
    • Cynomolgus
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDH6-070H Recombinant Human CDH6 Protein, HIS-tagged HEK293 HIS
    Human CDH6-071H Recombinant Human CDH6 Protein, Fc-tagged HEK293 Fc
    Human CDH6-0992H Recombinant Human CDH6 Protein, GST-Tagged Wheat Germ GST
    Human CDH6-110H Recombinant Human CDH6 protein, T7/His-tagged E.coli T7/His
    Human CDH6-2727HCL Recombinant Human CDH6 cell lysate Human Cell N/A
    Human CDH6-668H Recombinant Human CDH6 protein, His-tagged HEK293 His
    Mouse CDH6-1478MCL Recombinant Mouse CDH6 cell lysate Human Cell N/A
    Mouse Cdh6-593M Recombinant Mouse Cdh6 Protein, His-tagged NS0 His
    Mouse Cdh6-7411M Recombinant Mouse Cdh6, His tagged Human Cell His
    Rat CDH6-1098R Recombinant Rat CDH6 Protein, His-tagged HEK293 His
    Rat CDH6-1294R Recombinant Rat CDH6 Protein Mammalian Cell His
    Cynomolgus CDH6-1102C Recombinant Cynomolgus CDH6 Protein (Met1-Gly614), His-tagged HEK293 His
    Chicken CDH6-1154C Recombinant Chicken CDH6 Mammalian Cell His
    Zebrafish CDH6-2187Z Recombinant Zebrafish CDH6 Mammalian Cell His

    cdh6 involved in several pathways and played different roles in them. We selected most pathways cdh6 participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with cdh6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adherens junctions interactions CDH17; ANG; CDH4; CDH3; CTNNB2; CDH7; CDH12; CDH2; CTNNA1; JUP
    Cell junction organization CDH18; CDH8; CDH7; PARVB; CDH3; CADM2A; CLDN20; CDH12A; PLEC; JUPA
    Cell-Cell communication CDH12A; FERMT2; CD151; CDH3; CLDN4; SPTBN1; JUP; PVRL1A; CDH8; CDH24
    Cell-cell junction organization CDH11; F11R.2; PVRL1A; CDH7; JUP; CDH18; CTNND1; INADL; CDH13; CLDN16
    Neural Crest Differentiation TXLNB; TCF4; TFAP2B; TFAP2A; LHX1; CDH6; SOX5; OLIG3; DMBX1; PRTG

    cdh6 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cdh6 itself. We selected most functions cdh6 had, and list some proteins which have the same functions with cdh6. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding CELSR1; ANXA3B; NOTCH3; ATP2C1; ANXA5A; SLC25A23; EFEMP2A; FBN2B; CDHR1A; CETN1

    cdh6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdh6 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdh6.

    Butler, MG; Rafi, SK; et al. Whole Exome Sequencing in Females with Autism Implicates Novel and Candidate Genes. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 16:1312-1335(2015).
    Clay, MR; Halloran, MC; et al. Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition. DEVELOPMENT 141:2506-2515(2014).

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