cdh10

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cdh10

Official Full Name cadherin 10, type 2 (T2-cadherin)
Background This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the proteins homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.
Synonyms CDH10; cadherin 10, type 2 (T2-cadherin); cadherin-10; T2-cadherin
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • CHO
    • E.coli
    • Mammalian Cell
    • Tag :
    • Fc
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDH10-26741TH Recombinant Human CDH10, His-tagged E.coli His
    Human CDH10-41H Recombinant Human CDH10 protein, Fc-tagged CHO Fc
    Mouse CDH10-3163M Recombinant Mouse CDH10 Protein Mammalian Cell His
    Chicken CDH10-7144C Recombinant Chicken CDH10 Mammalian Cell His

    cdh10 involved in several pathways and played different roles in them. We selected most pathways cdh10 participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with cdh10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adherens junctions interactions CDH4; CTNNB1; CDH8; CDH24; CDH6; CTNNB2; JUP; ANG; CDH12; CADM2B
    Cell junction organization CDH12; CLDN7; CDH18; CDH24; COL17A1; DST; PLECA; ITGB1B.1; CLDN3; JUP
    Cell-Cell communication CDH8; SIRPA; CDH24; PVRL1A; PLECA; CADM2; KIRREL3; DST; INADL; JUPA
    Cell-cell junction organization CTNND1; CDH8; CDH24; CADM2; CADM2B; CDH17; CLDN7; JUP; CDH9; JUPA

    cdh10 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cdh10 itself. We selected most functions cdh10 had, and list some proteins which have the same functions with cdh10. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding PCLO; PCDHGA8; NELL2A; ITSN2B; ELTD1; ANXA1B; CCBE1; MMP13A; MYLPF; PCDHB7

    cdh10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdh10 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdh10.

    PTN; COPS6; Cdh1; CTNNB1

    An, CH; Je, EM; et al. Frameshift Mutations of Cadherin Genes DCHS2, CDH10 and CDH24 Genes in Gastric and Colorectal Cancers with High Microsatellite Instability. PATHOLOGY & ONCOLOGY RESEARCH 21:181-185(2015).
    Ahn, JW; Kim, HS; et al. Identification of somatic mutations in EGFR/KRAS/ALK-negative lung adenocarcinoma in never-smokers. GENOME MEDICINE 6:-(2014).

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