CDH12

  • Official Full Name

    cadherin 12, type 2 (N-cadherin 2)

  • Overview

    This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
  • Synonyms

    CDH12; cadherin 12, type 2 (N-cadherin 2); cadherin-12; Br cadherin; CDHB; Br-cadherin; N-cadherin 2; brain cadherin; brain-cadherin; neuronal cadherin 2; neural type cadherin 2; cadherin, neural type, 2; FLJ34857;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mouse
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CDH12-26803TH Recombinant Human CDH12 Wheat Germ N/A 99 amino acids
Human CDH12-2230H Recombinant Human CDH12, His tagged Human Cell His
Human CDH12-0973H Recombinant Human CDH12 Protein, GST-Tagged Wheat Germ GST
Human CDH12-2625HCL Recombinant Human CDH12 cell lysate Human Cell N/A
Human CDH12-3136HF Recombinant Full Length Human CDH12 Protein, GST-tagged In Vitro Cell Free System GST 794 amino acids
Human CAB11506MH Mouse Anti-Human Cadherin 12, Type 2 Monoclonal Antibody Mouse N/A
Human CDH12-2177H Recombinant Human CDH12 protein, His-tagged HEK293 His Met1-Ala605
Human CDH12-1256H Recombinant Human CDH12 Protein (56-605 aa), His-tagged E.coli His 56-605 aa
Human CDH12-1311H Recombinant Human CDH12 Protein (Phe421-Lys535), N-His tagged E.coli N-His Phe421-Lys535
Mouse CDH12-3165M Recombinant Mouse CDH12 Protein Mammalian Cell His
Mouse CDH12-1503M Recombinant Mouse CDH12 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CDH12-1503M-B Recombinant Mouse CDH12 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL21784HF Recombinant Full Length Human Cadherin-12(Cdh12) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (55-794)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CDH12 involved in several pathways and played different roles in them. We selected most pathways CDH12 participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adherens junctions interactionsCDH12;CTNND1;CTNNB1;CDH2;CADM2A;CDH18A;CDH3;CDH8;CTNNA1
Cell junction organizationCOL17A1;CDH12A;CDH18;CDH17;FERMT2;ANG;PLECA;CDH7;CDH8
Cell-Cell communicationKIRREL3;CDH12;PARVB;KIRREL;CDH17;FERMT2;PVRL1A;SKAP2;JUPA
Cell-cell junction organizationCLDN16;CDH9;CDH12;ANG;JUP;CLDN23;CLDN3;F11R.2;CDH10

CDH12 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH12 itself. We selected most functions CDH12 had, and list some proteins which have the same functions with CDH12. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingTTYH1;PCDH1GB9;PCDHGB2;CELSR2;FLG2;ZZEF1;RCV1;SYT7;MMP1A

CDH12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDH12 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDH12.

IGHG1

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