cdh17
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  • Official Full Name
  • cadherin 17, LI cadherin (liver-intestine)
  • Background
  • This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins.;The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a;transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal;tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral;absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological;organization of liver and intestine. Alternative splicing results in multiple transcript variants.
  • Synonyms
  • CDH17; cadherin 17, LI cadherin (liver-intestine); cadherin-17; cadherin; HPT 1; LI cadherin; LI-cadherin; cadherin-16; HPT-1 cadherin; liver-intestine cadherin; human peptide transporter 1; intestinal peptide-associated transporter HPT-1; human intestina
Cat.#:CDH17-1100CTag:HlgG1 Fc
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus CDH17 Protein (Met1-Met787), HlgG1 Fc-tagged
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Cat.#:CDH17-2043HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CDH17 Protein, His-tagged
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Cat.#:CDH17-0978HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CDH17 Protein, GST-Tagged
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Cat.#:CDH17-2094HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CDH17 protein, His & T7-tagged
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Cat.#:CDH17-29102THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human CDH17
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Cat.#:CDH17-3898HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CDH17, His tagged
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Cat.#:CDH17-1289RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CDH17 Protein
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Cat.#:CDH17-4342CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CDH17
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Cat.#:CDH17-9772ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CDH17
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Cat.#:CDH17-2032HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CDH17 cell lysate
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Cat.#:CDH17-1483RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat CDH17 cell lysate
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Involved Pathway

CDH17 involved in several pathways and played different roles in them. We selected most pathways CDH17 participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adherens junctions interactions
PTBP3; CTNNB2; CTNNB1; CDH18; CDH24; PVRL2L; JUPA; CDH9; CTNNA1; JUP
Cell junction organization
CDH12; TESK1; CDH12A; CTNND1; PARVB; PVRL1A; CDH3; ITGB1B.1; CDH6; CD151
Cell-Cell communication
KIRREL3L; FBLIM1; CDH18; JUPA; CDH13; CLDN16; CDH17; CDH9; PARVB; DSCAMA
Cell-cell junction organization
CDH24; JUP; CLDN20; ANG; CDH5; CDH12A; CDH10; CDH3; CDH4; JUPA

Protein Function

CDH17 has several biochemical functions, for example, calcium ion binding, proton-dependent oligopeptide secondary active transmembrane transporter activity, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH17 itself. We selected most functions CDH17 had, and list some proteins which have the same functions with CDH17. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein ITSN2; EPD; CRNN; EFHA1; MICU1; MYL1; SYT12; NKD2; MMP13A; PCDHGA11
Function proton-dependent oligopeptide secondary active transmembrane transporter activity
Related Protein CDH17; SLC15A1
Function transporter activity
Related Protein FABP1B.1; AQP12B; SLC16A10; ATP5G3; SLC2A15A; FABP6; CPNE6; AQP9A; SLC22A13; TIMM9

CDH17 Related Articles

Funakoshi, S; Shimizu, T; et al. BILL-Cadherin/Cadherin-17 Contributes to the Survival of Memory B Cells. PLOS ONE 10:-(2015).
Lin, ZH; Zhang, C; et al. Targeting Cadherin-17 Inactivates Ras/Raf/MEK/ERK Signaling and Inhibits Cell Proliferation in Gastric Cancer. PLOS ONE 9:-(2014).