cdh8

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cdh8

Official Full Name cadherin 8, type 2
Background This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the proteins homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
Synonyms CDH8; cadherin 8, type 2; cadherin-8; Nbla04261
    • Species :
    • Chicken
    • Human
    • Rat
    • Rhesus Macaque
    • Source :
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • Fc
    • Fc Chimera
    • His
    • GST
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDH8-0995H Recombinant Human CDH8 Protein, GST-Tagged Wheat Germ GST
    Human CDH8-160H Recombinant Human CDH8, Fc Chimera NS0 Fc Chimera
    Human CDH8-26742TH Recombinant Human CDH8 Wheat Germ N/A
    Human CDH8-2738HCL Recombinant Human CDH8 cell lysate Human Cell N/A
    Human CDH8-3148H Recombinant Human CDH8 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CDH8-602H Recombinant Human CDH8, His tagged Human Cell His
    Human CDH8-625H Recombinant Human CDH8 Mammalian Cell His
    Rat Cdh8-24R Recombinant Rat Cdh8, LEVLFQ tagged Human Cell Fc
    Rat Cdh8-8760R Recombinant Rat Cdh8, His tagged Human Cell Fc/His
    Rat CDH8-991RCL Recombinant Rat CDH8 cell lysate Human Cell N/A
    Rhesus Macaque CDH8-777R Recombinant Rhesus monkey CDH8 Protein, His-tagged Mammalian Cell His
    Chicken CDH8-3730C Recombinant Chicken CDH8 Mammalian Cell His

    cdh8 involved in several pathways and played different roles in them. We selected most pathways cdh8 participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with cdh8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adherens junctions interactions CDH18A; JUP; JUPA; CDH12A; CDH4; CDH13; CTNNB2; CDH18; CDH8; PVRL1A
    Cell junction organization CDH18; CDH11; CLDN23; CDH24; DST; FBLIM1; LIMS1; CTNND1; PVRL2L; PARVB
    Cell-Cell communication CDH18; JUP; CDH6; NPHS1; CD151; JUPA; RSU1; CDH8; CADM2; CLDN23
    Cell-cell junction organization CDH24; CADM2; CDH18; CLDN4; CDH6; CDH5; PVRL2L; JUP; CDH8; CDH17

    cdh8 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cdh8 itself. We selected most functions cdh8 had, and list some proteins which have the same functions with cdh8. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding PCDHB11; CBL; PCDH2G17; PCDHGC3; HSPA5; TBC1D8B; DSC2; SYTL2; CABP4; PCDHB13

    cdh8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdh8 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdh8.

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