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CDH8

  • Official Full Name

    cadherin 8, type 2

  • Overview

    This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the proteins homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
  • Synonyms

    CDH8; cadherin 8, type 2; cadherin-8; Nbla04261;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Fc
  • Fc Chimera
  • Fc|His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CDH8-160H Active Recombinant Human CDH8, Fc Chimera Mammalian cells Fc Chimera
Human CDH8-0995H Recombinant Human CDH8 Protein, GST-Tagged Wheat Germ GST
Human CDH8-26742TH Recombinant Human CDH8 Wheat Germ N/A 100 amino acids
Human CDH8-602H Recombinant Human CDH8 protein, His-tagged HEK293 His Met1-Met621
Human CDH8-625H Recombinant Human CDH8 Mammalian Cell His
Human CDH8-2738HCL Recombinant Human CDH8 cell lysate Human Cell N/A
Human CDH8-0271H Recombinant Human CDH8 Protein (Ala30-Met621), C-His-tagged Mammalian cells C-His Ala30-Met621
Human CDH8-3148H Recombinant Human CDH8 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CDH8-3152HF Recombinant Full Length Human CDH8 Protein, GST-tagged In Vitro Cell Free System GST 799 amino acids
Human CDH8-4940H Recombinant Human CDH8 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CDH8-178H-B Recombinant Human CDH8 Protein Pre-coupled Magnetic Beads HEK293
Human CDH8-178H Recombinant Human CDH8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Cdh8-863M Recombinant Mouse Cdh8 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat Cdh8-8760R Recombinant Rat Cdh8, His tagged Human Cell Fc/His
Rat Cdh8-24R Recombinant Rat Cdh8, LEVLFQ tagged Human Cell Fc
Rat CDH8-991RCL Recombinant Rat CDH8 cell lysate Human Cell N/A
Rat CDH8-1039R Recombinant Rat CDH8 protein(Met1-Met621) HEK293 N/A Met1-Met621
Rat CDH8-3373R Recombinant Rat CDH8 protein(Met1-Met621), His-tagged HEK293 C-His Met1-Met621
Homo sapiens (Human) RFL26641HF Recombinant Full Length Human Cadherin-8(Cdh8) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (62-799)
Mus musculus (Mouse) RFL18244MF Recombinant Full Length Mouse Cadherin-8(Cdh8) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (62-799)
Rattus norvegicus (Rat) RFL26735RF Recombinant Full Length Rat Cadherin-8(Cdh8) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (62-799)
Rhesus Macaque CDH8-777R Recombinant Rhesus monkey CDH8 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CDH8-603R Recombinant Rhesus Macaque CDH8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CDH8-603R-B Recombinant Rhesus Macaque CDH8 Protein Pre-coupled Magnetic Beads HEK293
Chicken CDH8-3730C Recombinant Chicken CDH8 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CDH8 involved in several pathways and played different roles in them. We selected most pathways CDH8 participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDH8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adherens junctions interactionsJUP;CDH8;CTNNB2;CTNND1;CDH10A;CDH9;PVRL2L;CDH4;PVRL1A
Cell junction organizationCOL17A1A;CDH12A;CDH18;CDH2;CLDN16;CDH5;CTNND1;CDH18A;CDH13
Cell-Cell communicationDSCAM;PLEC;CLDN20;CDH10;CD151;CDH17;FERMT2;CLDN7;CDH9
Cell-cell junction organizationJUPA;CDH24;CDH11;CLDN23;ANG;CDH18;CDH6;CDH10;PVRL1A

CDH8 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDH8 itself. We selected most functions CDH8 had, and list some proteins which have the same functions with CDH8. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingMMP13;THBS4A;SPARC;NOTCH1A;CGREF1;HMCN1;ITPR3;FBN1;FBLN2

CDH8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDH8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDH8.

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