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Official Full Name cadherin 18, type 2
Background This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
Synonyms CDH18; cadherin 18, type 2; cadherin-18; CDH14; EY CADHERIN; cadherin-14; ey-cadherin; cadherin-like 24; CDH24; CDH14L
    • Species :
    • Cynomolgus Monkey
    • Human
    • Source :
    • E.coli
    • Human Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDH18-0979H Recombinant Human CDH18 Protein, GST-Tagged Wheat Germ GST
    Human CDH18-11034H Recombinant Human CDH18, GST-tagged E.coli GST
    Human CDH18-47H Recombinant Human CDH18 protein, T7/His-tagged E.coli T7/His
    Cynomolgus Monkey CDH18-765CCL Recombinant Cynomolgus CDH18 cell lysate Human Cell N/A
    Cynomolgus Monkey CDH18-85C Recombinant Cynomolgus CDH18, His tagged Human Cell His

    cdh18 involved in several pathways and played different roles in them. We selected most pathways cdh18 participated on our site, such as Adherens junctions interactions, Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with cdh18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adherens junctions interactions CADM2B; CTNNB1; JUPA; CDH8; CDH4; CDH18; PVRL1A; CDH7; CDH18A; CDH2
    Cell junction organization CDH18A; CLDN23; CTNND1; CDH2; PLECA; PVRL2L; CD151; CADM2A; CDH5; CDH18
    Cell-Cell communication CDH10; CDH4; CADM2; NPHS1; CDH24; CDH18A; CDH13; LIMS1; SIRPA; CADM2B
    Cell-cell junction organization CADM2B; JUPA; CDH12A; CDH17; PVRL2L; CDH18A; CDH12; CLDN16; CLDN7; CDH11

    cdh18 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cdh18 itself. We selected most functions cdh18 had, and list some proteins which have the same functions with cdh18. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding EDIL3; CELSR3; CDHR1; MYL2; PON1; EFHC2; PKD1L3; S100A16; FBLN7; VCANB

    cdh18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdh18 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdh18.


    Mackowiak, II; Gentile, LB; et al. E-cadherin in canine mast cell tumors: Decreased expression and altered subcellular localization in Grade 3 tumors. VETERINARY JOURNAL 194:405-411(2012).
    Yoshimura, K; Meckel, KF; et al. Integrin alpha 2 Mediates Selective Metastasis to the Liver. CANCER RESEARCH 69:7320-7328(2009).

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