Recombinant Human CES1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human CES1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : CES1-5361H
Product Overview : CES1 MS Standard C13 and N15-labeled recombinant protein (NP_001020366) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 62.59 kDa
AA Sequence : MWLRAFILAT LSASAAWAGH PSSPPVVDTV HGKVLGKFVS LEGFAQPVAI FLGIPFAKPP LGPLRFTPPQ PAEPWSFVKN ATSYPPMCTQ DPKAGQLLSE LFTNRKENIP LKLSEDCLYL NIYTPADLTK KNRLPVMVWI HGGGLMVGAA STYDGLALAA HENVVVVTIQ YRLGIWGFFS TGDEHSRGNW GHLDQVAALR WVQDNIASFG GNPGSVTIFG ESAGGESVSV LVLSPLAKNL FHRAISESGV ALTSVLVKKG DVKPLAEQIA ITAGCKTTTS AVMVHCLRQK TEEELLETTL KMKFLSLDLQ GDPRESQPLL GTVIDGMLLL KTPEELQAER NFHTVPYMVG INKQEFGWLI PMQLMSYPLS EGQLDQKTAM SLLWKSYPLV CIAKELIPEA TEKYLGGTDD TVKKKDLFLD LIADVMFGVP SVIVARNHRD AGAPTYMYEF QYRPSFSSDM KPKTVIGDHG DELFSVFGAP FLKEGASEEE IRLSKMVMKF WANFARNGNP NGEGLPHWPE YNQKEGYLQI GANTQAAQKL KDKEVAFWTN LFAKKAVEKP PQTEHIELTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : CES1 carboxylesterase 1 [ Homo sapiens (human) ]
Official Symbol : CES1
Synonyms : CES1; carboxylesterase 1; carboxylesterase 1 (monocyte/macrophage serine esterase 1); liver carboxylesterase 1; CEH; CES1A1; CES1A2; CES2; HMSE; HMSE1; human monocyte/macrophage serine esterase 1; SES1; egasyn; serine esterase 1; retinyl ester hydrolase; cocaine carboxylesterase; triacylglycerol hydrolase; carboxylesterase 2 (liver); brain carboxylesterase hBr1; cholesteryl ester hydrolase; monocyte/macrophage serine esterase; methylumbelliferyl-acetate deacetylase 1; acyl coenzyme A:cholesterol acyltransferase; acyl-coenzyme A:cholesterol acyltransferase; REH; TGH; ACAT; PCE-1; MGC117365;
Gene ID : 1066
mRNA Refseq : NM_001025195
Protein Refseq : NP_001020366
MIM : 114835
UniProt ID : P23141

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