|Official Full Name||carboxylesterase 2E|
|Background||carboxylesterase/lipase family. Mammalian carboxylesterases (CES) exhibit broad substrate specificities, catalyse hydrolytic and transesterification reactions with a wide range of drugs and xenobiotics and are widely distributed in the body. Four CES classes have been previously described, namely CES1 (major liver form); CES2 (major intestinal form); CES3 (highest activity in the colon); and CES5, a secreted enzyme found in mammalian kidney and male reproductive fluids. Roles for CES5 may also include regulating urinary levels of male cat pheromones; catalysing lipid transfer reactions within mammalian male reproductive fluids; and protecting neural tissue from drugs and xenobiotics.|
|Synonyms||Ces2e; carboxylesterase 2E; Ces5; 9030624L02Rik; carboxylesterase 5; EC 18.104.22.168|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ces2e involved in several pathways and played different roles in them. We selected most pathways ces2e participated on our site, such as Drug metabolism - other enzymes, which may be useful for your reference. Also, other proteins which involved in the same pathway with ces2e were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Drug metabolism - other enzymes||UPP1; UCK1; UGT1A7C; UGT1A2; Nat3; PNAT10; UGT2B7; UGT2A3; CES2; GUSB|
ces2e has several biochemical functions, for example, carboxylic ester hydrolase activity, hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ces2e itself. We selected most functions ces2e had, and list some proteins which have the same functions with ces2e. You can find most of the proteins on our site.
|carboxylic ester hydrolase activity||ABHD11; NCEH1; CES1; PNPLA7; ACOT12; CES3A; ACOT1; ACOT2; CES2; ABHD4|
|hydrolase activity||OTUD5A; NUDT8; EAR2; PLA2G4AA; MCPT1; SNRNP200; ENDOU2; ABHD6B; CHD6; INPP5L|
ces2e has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ces2e here. Most of them are supplied by our site. Hope this information will be useful for your research of ces2e.