• Official Full Name

    carboxylesterase 5A

  • Overview

    This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES5, is predominantly expressed in peripheral tissues, including brain, kidney, lung and testis. It encodes a secreted enzyme. Because of high levels in the urine of male domestic cats, this enzyme is also called cauxin (carboxylesterase-like urinary excreted protein). The enzyme functions in regulating the production of a pheromone precursor and may contribute to lipid and cholesterol transfer processes within male reproductive fluids. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    CES5A; carboxylesterase 5A; carboxylesterase 7 , CES7; CAUXIN; CES4C1; CES5; FLJ31547; Carboxylesterase 5; Carboxylesterase 7; Carboxylesterase like urinary excreted protein; Carboxylesterase like urinary excreted protein homolog; CES 7; EC; carboxylesterase-like urinary excreted protein homolog; CES7;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CES5A-5238H Recombinant Human CES5A Protein, GST-tagged Wheat Germ GST
Human CES5A-7563HCL Recombinant Human CES7 293 Cell Lysate HEK293 N/A
Human CES5A-752H Recombinant Human CES5A Protein, His&GST-tagged E.coli N-His&GST His383-Phe570
Human CES5A-1825H Recombinant Human CES5A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CES5A-3898HF Recombinant Full Length Human CES5A Protein, GST-tagged In Vitro Cell Free System GST 525 amino acids
Mouse CES5A-2231MCL Recombinant Mouse CES5A cell lysate Human Cell N/A
Mouse Ces5a-2125M Recombinant Mouse Ces5a Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat CES5A-1351R Recombinant Rat CES5A Protein Mammalian Cell His
Rat CES5A-1009R-B Recombinant Rat CES5A Protein Pre-coupled Magnetic Beads HEK293
Rat CES5A-1009R Recombinant Rat CES5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CES5A-823R Recombinant Rhesus monkey CES5A Protein, His-tagged Mammalian Cell His
Rhesus Macaque CES5A-649R-B Recombinant Rhesus Macaque CES5A Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CES5A-649R Recombinant Rhesus Macaque CES5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CES5A involved in several pathways and played different roles in them. We selected most pathways CES5A participated on our site, such as E2F transcription factor network, Phase I, non P450, retinol biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CES5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
E2F transcription factor networkTRIM28;HIC1;HBP1;RYBP;CES5A;CES1;E2F6;CEBPA;SMARCA2
Phase I, non P450
retinol biosynthesisDHRS9;RBP5;DHRS4;CES5A

CES5A has several biochemical functions, for example, sterol esterase activity, triglyceride lipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CES5A itself. We selected most functions CES5A had, and list some proteins which have the same functions with CES5A. You can find most of the proteins on our site.

Function Related Protein
sterol esterase activityCES5A;CES1D;LIPA;CEL.1;Cel;CES1;CES3
triglyceride lipase activityPNPLA4;PNPLA2;PNLIPRP3;LIPC;LIPF;PNPLA3;CES1;CEL.1;CES1D

CES5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CES5A here. Most of them are supplied by our site. Hope this information will be useful for your research of CES5A.

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