ces2

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ces2

Official Full Name carboxylesterase 2
Background This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010]
Synonyms CES2; carboxylesterase 2; iCE; CE-2; PCE-2; CES2A1; cocaine esterase; hCE-2; carboxylesterase 2 (intestine, liver); methylumbelliferyl-acetate deacetylase 2; intestinal carboxylesterase; liver carboxylesterase-2;
    • Species :
    • Human
    • Zebrafish
    • Source :
    • BTI Insect Cell
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CES2-107H Recombinant Human CES2 Protein E. coli
    Human CES2-1139H Recombinant Human CES2, His tagged Human Cell His
    Human CES2-1140H Recombinant Human CES2 BTI Insect Cell N/A
    Human CES2-1141H Recombinant Human CES2, MYC/DDK-tagged HEK293 Myc/DDK
    Human CES2-1149H Recombinant Human CES2 Protein, GST-Tagged Wheat Germ GST
    Human CES2-2139HCL Recombinant Human CES2 cell lysate Human Cell N/A
    Human CES2-22H Recombinant Human CES2 Protein, His-tagged NS0 His
    Human CES2-4690H Recombinant Human CES2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CES2-4904H Recombinant Human CES2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CES2-896H Recombinant Human CES2 E.coli N/A
    Zebrafish CES2-4641Z Recombinant Zebrafish CES2 Mammalian Cell His

    ces2 involved in several pathways and played different roles in them. We selected most pathways ces2 participated on our site, such as Drug metabolism - other enzymes, which may be useful for your reference. Also, other proteins which involved in the same pathway with ces2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Drug metabolism - other enzymes IMPDH1A; CES2; TPMT; UGT1A6A; NAT; PNAT10; NAT1; UGT1A6; GMPS; TYMP

    ces2 has several biochemical functions, for example, carboxylic ester hydrolase activity, methylumbelliferyl-acetate deacetylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ces2 itself. We selected most functions ces2 had, and list some proteins which have the same functions with ces2. You can find most of the proteins on our site.

    Function Related Protein
    carboxylic ester hydrolase activity ABHD2A; LIPH; CES1; ACOT7; LYPLA2; NCEH1; Cel; ACOT9; LYPLAL1; CES2
    methylumbelliferyl-acetate deacetylase activity CES2; CES1; ESD

    ces2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ces2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ces2.

    ispH; 1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate

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