• Official Full Name

    carboxylesterase 3

  • Overview

    This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.
  • Synonyms

    CES3; carboxylesterase 3; carboxylesterase 3 (brain); brain carboxylesterase BR3; ES31; esterase 31; FLJ21736; ES3; CES 3; Liver carboxylesterase 31 homolog;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Zebrafish
  • E.coli
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CES3-899H Recombinant Human CES3, His tagged Human Cell His
Human CES3-898H Recombinant Human CES3, GST-tagged E.coli GST
Human CES3-1151H Recombinant Human CES3 Protein, GST-Tagged Wheat Germ GST
Human CES3-636HCL Recombinant Human CES3 cell lysate N/A
Human CES3-3264HF Recombinant Full Length Human CES3 Protein, GST-tagged In Vitro Cell Free System GST 568 amino acids
Human CES3-3198H Recombinant Human CES3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CES3-897H Recombinant Human CES3 protein, His-tagged E.coli His Ser398~Gln568
Human CES3-1922HFL Recombinant Full Length Human CES3 Protein, C-Flag-tagged Mammalian cells Flag
Human CES3-580H Recombinant Human CES3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CES3-580H-B Recombinant Human CES3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CES3-4035Z Recombinant Zebrafish CES3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CES3 involved in several pathways and played different roles in them. We selected most pathways CES3 participated on our site, such as E2F transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with CES3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
E2F transcription factor networkPRMT5;YY1;CES1;SMARCA2;CES3;HBP1;RYBP;E2F4;CEBPA

CES3 has several biochemical functions, for example, sterol esterase activity, triglyceride lipase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CES3 itself. We selected most functions CES3 had, and list some proteins which have the same functions with CES3. You can find most of the proteins on our site.

Function Related Protein
sterol esterase activityLIPA;CEL.1;Cel;CES3;CES5A;CES1;CES1D
triglyceride lipase activityPNPLA2;PNLIPRP2;PNLIPRP3;PNLIPRP1;PNLIP;LPL;CEL.1;LIPE;Cel

CES3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CES3 here. Most of them are supplied by our site. Hope this information will be useful for your research of CES3.


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