Recombinant Human CLDN4 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | CLDN4-4751H |
Product Overview : | CLDN4 MS Standard C13 and N15-labeled recombinant protein (NP_001296) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
- Download
Description : | The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 22.1 kDa |
AA Sequence : | MASMGLQVMGIALAVLGWLAVMLCC ALPMWRVTAFIGSNIVTSQTIWEGL WMNCVVQSTGQMQCKVYDSLLALPQ DLQAARALVIISIIVAALGVLLSVV GGKCTNCLEDESAKAKTMIVAGVVF LLAGLMVIVPVSWTAHNIIQDFYNP LVASGQKREMGASLYVGWAASGLLL LGGGLLCCNCPPRTDKPYSAKYSAA RSAAASNYVTRTRPLEQKLISEEDL AANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | CLDN4 claudin 4 [ Homo sapiens (human) ] |
Official Symbol : | CLDN4 |
Synonyms : | CLDN4; claudin 4; CPETR, CPETR1; claudin-4; Clostridium perfringens enterotoxin receptor 1; CPE R; hCPE R; WBSCR8; Williams Beuren syndrome chromosomal region 8 protein; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein; CPER; CPE-R; CPETR; CPETR1; hCPE-R; |
Gene ID : | 1364 |
mRNA Refseq : | NM_001305 |
Protein Refseq : | NP_001296 |
MIM : | 602909 |
UniProt ID : | O14493 |
Products Types
◆ Recombinant Protein | ||
CLDN4-150H | Recombinant Human CLDN4 Protein, Myc/DDK-tagged | +Inquiry |
Cldn4-901M | Recombinant Mouse Cldn4 Protein, MYC/DDK-tagged | +Inquiry |
CLDN4-1443H | Recombinant Human CLDN4 Protein, GST-tagged | +Inquiry |
CLDN4-612H | Recombinant Human CLDN4 Protein, His (Fc)-Avi-tagged | +Inquiry |
CLDN4-1733M | Recombinant Mouse CLDN4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CLDN4-7462HCL | Recombinant Human CLDN4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionInhibiting CLDN4 function could enhance the efficacy of existing cancer therapies and potentially lead to the development of new treatment strategies.
CLDN4 is involved in regulating the entry of certain pathogens into host cells, making it a potential target for the development of antiviral and antibacterial therapies.
Research is underway to explore the potential of targeting CLDN4 to modulate tissue barrier function and alleviate the symptoms of autoimmune diseases.
Monitoring CLDN4 levels and function may provide valuable insights into the progression of IBD and help in the development of targeted therapies.
CLDN4 is also being studied in the context of kidney disease, skin disorders, and neurodegenerative diseases due to its role in maintaining tissue barrier function.
Customer Reviews (3)
Write a reviewThe CLDN4 protein showcases outstanding quality, ensuring its suitability for addressing my experimental requirements effectively.
the manufacturer's dedication to excellent technical support assures me that any challenges or obstacles I encounter will be swiftly resolved.
Its top-notch purity and integrity instill confidence in obtaining precise and reliable data, thereby enabling significant advancements in my research.
Ask a Question for All CLDN4 Products
Required fields are marked with *
My Review for All CLDN4 Products
Required fields are marked with *
Inquiry Basket