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Official Full Name claudin 10
Background This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.
Synonyms CLDN10; claudin 10; claudin-10; CPETRL3; OSP L; OSP-like protein; OSP-L
    • Species :
    • Chicken
    • Human
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CLDN10-1426H Recombinant Human CLDN10 Protein, GST-tagged Wheat Germ GST
    Human CLDN10-362HCL Recombinant Human CLDN10 cell lysate N/A
    Chicken CLDN10-5129C Recombinant Chicken CLDN10 Mammalian Cell His
    Chicken CLDN10-5130C Recombinant Chicken CLDN10 Mammalian Cell His
    Chicken CLDN10-5131C Recombinant Chicken CLDN10 Mammalian Cell His

    cldn10 involved in several pathways and played different roles in them. We selected most pathways cldn10 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with cldn10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) Itgam&Itgb2; BF2; HLA-DRB3; ALCAM; VTCN1; CD274; CLDN15LB; CLDN20; CNTNAP2; NRXN2
    Tight junction ACTN3B; HRAS; SRC; MYH11A; PARD6B; EPB41L2; YES1; SHROOM4; MYH6; PTENB
    Leukocyte transendothelial migration MYLPF; NCF2; JAM2; CLDN6; CXCR4; ACTB; CYBA; TXK; CLDN18; MYL5
    Hepatitis C TYK2; MAPK1; OAS1B; PPP2R2A; MAVS; GSK3B; AKT2; TNF; MAPK11; IL-8

    cldn10 has several biochemical functions, for example, identical protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cldn10 itself. We selected most functions cldn10 had, and list some proteins which have the same functions with cldn10. You can find most of the proteins on our site.

    Function Related Protein
    identical protein binding GLUL; SMAD4; KDM6A; ATXN3; AGER; MLL1; ALDOA; SDF4; MICALL1; MAP1S
    structural molecule activity CDC42SE2; VCL; CLDN16; CLDN12; SEPT7; JUPA; EPB41L1; KRT71; ODF2; KRT84

    cldn10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cldn10 here. Most of them are supplied by our site. Hope this information will be useful for your research of cldn10.

    Ghosn, J; Fouquet, B; et al. Claudin-1 Gene Variants and Susceptibility to Hepatitis C Infection in HIV-1 Infected Intravenous Drug Users (an ANRS Case-Control Study). JOURNAL OF MEDICAL VIROLOGY 87:619-624(2015).
    Hong, LC; Wu, YG; et al. Overexpression of the cell adhesion molecule claudin-9 is associated with invasion in pituitary oncocytomas. HUMAN PATHOLOGY 45:2423-2429(2014).

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