CLDN10
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Official Full Name
claudin 10
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Overview
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined. -
Synonyms
CLDN10; claudin 10; claudin-10; CPETRL3; OSP L; OSP-like protein; OSP-L;
- Recombinant Proteins
- Cell & Tissue Lysates
- Bos taurus (Bovine)
- Chicken
- Homo sapiens (Human)
- Human
- Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
- E.coli expression system
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | CLDN10-1426H | Recombinant Human CLDN10 Protein, GST-tagged | Wheat Germ | GST | ||
Human | CLDN10-362HCL | Recombinant Human CLDN10 cell lysate | N/A | |||
Human | CLDN10-2038HF | Recombinant Full Length Human CLDN10 Protein, GST-tagged | In Vitro Cell Free System | GST | 228 amino acids | |
Bos taurus (Bovine) | RFL32998BF | Recombinant Full Length Bovine Claudin-10(Cldn10) Protein, His-Tagged | E.coli expression system | His | Full Length (1-231) | |
Homo sapiens (Human) | RFL12169HF | Recombinant Full Length Human Claudin-10(Cldn10) Protein, His-Tagged | E.coli expression system | His | Full Length (1-228) | |
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) | RFL16102PF | Recombinant Full Length Pongo Abelii Claudin-10(Cldn10) Protein, His-Tagged | E.coli expression system | His | Full Length (1-228) | |
Chicken | CLDN10-5129C | Recombinant Chicken CLDN10 | Mammalian Cell | His | ||
Chicken | CLDN10-5130C | Recombinant Chicken CLDN10 | Mammalian Cell | His | ||
Chicken | CLDN10-5131C | Recombinant Chicken CLDN10 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- CLDN10 Related Articles
- CLDN10 Related Research Area
CLDN10 involved in several pathways and played different roles in them. We selected most pathways CLDN10 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLDN10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Cell adhesion molecules (CAMs) | MHC2DAB;PTPRM;LRRC4;PVRL2;HLA-DOB;JAM3;NRXN3A;HLA-DRB3;CLDNA |
Tight junction | CLDN11B;CLDN2;MYH1;ACTG1;MPP5;GNAI2A;CRB3;PARD3;CLDNJ |
Leukocyte transendothelial migration | CLDN4;PECAM1;PIK3R2;VCL;RAC2;AASS;RAP1A;MSN;BCAR1 |
Hepatitis C | PDPK1;IFIT1;MAPK9;IFN-a;IRF7;MAPK1;MAPK12;OAS3;IFNA17 |
CLDN10 has several biochemical functions, for example, identical protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLDN10 itself. We selected most functions CLDN10 had, and list some proteins which have the same functions with CLDN10. You can find most of the proteins on our site.
Function | Related Protein |
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identical protein binding | AMOTL2;NOL3;LYZ1;ATL2;DAPK1;CEACAM5;PPPDE2;DACT3;CLDNG |
structural molecule activity | SNTB1;KRT71;EIF3A;CDC42SE2;PNN;LELP1;LAMB1;EPB41L3B;TUBB |
CLDN10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLDN10 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLDN10.
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