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CLDN10

  • Official Full Name

    claudin 10

  • Overview

    This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.
  • Synonyms

    CLDN10; claudin 10; claudin-10; CPETRL3; OSP L; OSP-like protein; OSP-L;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Bos taurus (Bovine)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
  • E.coli expression system
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CLDN10-1426H Recombinant Human CLDN10 Protein, GST-tagged Wheat Germ GST
Human CLDN10-362HCL Recombinant Human CLDN10 cell lysate N/A
Human CLDN10-2038HF Recombinant Full Length Human CLDN10 Protein, GST-tagged In Vitro Cell Free System GST 228 amino acids
Bos taurus (Bovine) RFL32998BF Recombinant Full Length Bovine Claudin-10(Cldn10) Protein, His-Tagged E.coli expression system His Full Length (1-231)
Homo sapiens (Human) RFL12169HF Recombinant Full Length Human Claudin-10(Cldn10) Protein, His-Tagged E.coli expression system His Full Length (1-228)
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RFL16102PF Recombinant Full Length Pongo Abelii Claudin-10(Cldn10) Protein, His-Tagged E.coli expression system His Full Length (1-228)
Chicken CLDN10-5129C Recombinant Chicken CLDN10 Mammalian Cell His
Chicken CLDN10-5130C Recombinant Chicken CLDN10 Mammalian Cell His
Chicken CLDN10-5131C Recombinant Chicken CLDN10 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CLDN10 Related Articles
  • CLDN10 Related Research Area

CLDN10 involved in several pathways and played different roles in them. We selected most pathways CLDN10 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLDN10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)MHC2DAB;PTPRM;LRRC4;PVRL2;HLA-DOB;JAM3;NRXN3A;HLA-DRB3;CLDNA
Tight junctionCLDN11B;CLDN2;MYH1;ACTG1;MPP5;GNAI2A;CRB3;PARD3;CLDNJ
Leukocyte transendothelial migrationCLDN4;PECAM1;PIK3R2;VCL;RAC2;AASS;RAP1A;MSN;BCAR1
Hepatitis CPDPK1;IFIT1;MAPK9;IFN-a;IRF7;MAPK1;MAPK12;OAS3;IFNA17

CLDN10 has several biochemical functions, for example, identical protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLDN10 itself. We selected most functions CLDN10 had, and list some proteins which have the same functions with CLDN10. You can find most of the proteins on our site.

Function Related Protein
identical protein bindingAMOTL2;NOL3;LYZ1;ATL2;DAPK1;CEACAM5;PPPDE2;DACT3;CLDNG
structural molecule activitySNTB1;KRT71;EIF3A;CDC42SE2;PNN;LELP1;LAMB1;EPB41L3B;TUBB

CLDN10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLDN10 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLDN10.

Ghosn, J; Fouquet, B; et al. Claudin-1 Gene Variants and Susceptibility to Hepatitis C Infection in HIV-1 Infected Intravenous Drug Users (an ANRS Case-Control Study). JOURNAL OF MEDICAL VIROLOGY 87:619-624(2015).
Hong, LC; Wu, YG; et al. Overexpression of the cell adhesion molecule claudin-9 is associated with invasion in pituitary oncocytomas. HUMAN PATHOLOGY 45:2423-2429(2014).
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