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Official Full Name claudin 19
Background The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms CLDN19; claudin 19; claudin-19; CLDN 19; HOMG5
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CLDN19-1436H Recombinant Human CLDN19 Protein, GST-tagged Wheat Germ GST
    Human CLDN19-2623H Recombinant Human CLDN19 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CLDN19-3245H Recombinant Human CLDN19 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CLDN19-636H Recombinant Human CLDN19 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Cldn19-2179M Recombinant Mouse Cldn19 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat CLDN19-1434R Recombinant Rat CLDN19 Protein Mammalian Cell His
    Zebrafish CLDN19-2487Z Recombinant Zebrafish CLDN19 Mammalian Cell His

    cldn19 involved in several pathways and played different roles in them. We selected most pathways cldn19 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with cldn19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) HLA-DOA; MHC2DAB; CLDN18; CD58; Icosl; ITGB1; HLA-DPA1; NRXN1; MHC1UEA; CLDN3
    Tight junction CLDN2; GNAI1; RHOA; CLDN9; SMYHC1; MYH1C; MYL2; ACTN4; EPB41L1; HCLS1

    cldn19 has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cldn19 itself. We selected most functions cldn19 had, and list some proteins which have the same functions with cldn19. You can find most of the proteins on our site.

    Function Related Protein
    structural molecule activity CLDN12; COL4A3; Sprr2i; KRT1; FGB; CLDN9; LMNA; SEMG2; SNTG1; ASPH

    cldn19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cldn19 here. Most of them are supplied by our site. Hope this information will be useful for your research of cldn19.

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