CLDN19

  • Official Full Name

    claudin 19

  • Overview

    The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
  • Synonyms

    CLDN19; claudin 19; claudin-19; CLDN 19; HOMG5;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Zebrafish
  • E.coli expression system
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CLDN19-1436H Recombinant Human CLDN19 Protein, GST-tagged Wheat Germ GST
Human CLDN19-3245H Recombinant Human CLDN19 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CLDN19-636H Recombinant Human CLDN19 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CLDN19-2623H Recombinant Human CLDN19 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CLDN19-2048HF Recombinant Full Length Human CLDN19 Protein, GST-tagged In Vitro Cell Free System GST 211 amino acids
Mouse Cldn19-2179M Recombinant Mouse Cldn19 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat CLDN19-1434R Recombinant Rat CLDN19 Protein Mammalian Cell His
Rat CLDN19-1092R Recombinant Rat CLDN19 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CLDN19-1092R-B Recombinant Rat CLDN19 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL6224HF Recombinant Full Length Human Claudin-19(Cldn19) Protein, His-Tagged E.coli expression system His Full Length (1-224)
Mus musculus (Mouse) RFL9353MF Recombinant Full Length Mouse Claudin-19(Cldn19) Protein, His-Tagged E.coli expression system His Full Length (1-224)
Rattus norvegicus (Rat) RFL29670RF Recombinant Full Length Rat Claudin-19(Cldn19) Protein, His-Tagged E.coli expression system His Full Length (1-224)
Zebrafish CLDN19-2487Z Recombinant Zebrafish CLDN19 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CLDN19 involved in several pathways and played different roles in them. We selected most pathways CLDN19 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLDN19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)CDH5;NRXN3;Itgam&Itgb2;ITGAL;VCAN;ICOS;NTNG1;OCLN;CADM3
Tight junctionCLDNC;MYH10;CLDNB;MLLT4;MYH7B;MYH9A;PRKCZ;CDC42L2;EPB41

CLDN19 has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CLDN19 itself. We selected most functions CLDN19 had, and list some proteins which have the same functions with CLDN19. You can find most of the proteins on our site.

Function Related Protein
structural molecule activityKRT81;TUBG2;TUBGCP3;KRTAP3-3;EPB41L1;KRT32;CDC42SE2;KRT6A;KRT4

CLDN19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLDN19 here. Most of them are supplied by our site. Hope this information will be useful for your research of CLDN19.

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