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Official Full Name claudin 7
Background This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]
Synonyms CLDN7; claudin 7; CLDN-7; CEPTRL2; CPETRL2; Hs.84359; claudin-1; claudin-7; clostridium perfringens enterotoxin receptor-like 2;
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CLDN7-11299H Recombinant Human CLDN7, GST-tagged E.coli GST
    Human CLDN7-1446H Recombinant Human CLDN7 Protein, GST-tagged Wheat Germ GST
    Human CLDN7-27069TH Recombinant Human CLDN7 Wheat Germ N/A
    Human CLDN7-7459HCL Recombinant Human CLDN7 293 Cell Lysate HEK293 N/A
    Mouse CLDN7-3541M Recombinant Mouse CLDN7 Protein Mammalian Cell His

    cldn7 involved in several pathways and played different roles in them. We selected most pathways cldn7 participated on our site, such as Cell adhesion molecules (CAMs), Cell junction organization, Cell-Cell communication, which may be useful for your reference. Also, other proteins which involved in the same pathway with cldn7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) HLA-G; HLA-DRB1; F11R; CD276; L1CAM; JAM2A; CLDNJ; VCAN; CNTN1A; CLDN2
    Cell junction organization TESK1; INADL; CD151; PVRL2L; CDH8; CDH5; PARVB; FERMT2; CLDN7; PLEC
    Cell-Cell communication DSCAM; CLDN3; CDH10A; DSCAML1; CTNND1; KIRREL; JUP; RSU1; TESK1; CDH18A
    Cell-cell junction organization ANG; CTNND1; CDH10A; CLDN16; CDH7; CLDN4; CDH6; CADM2A; CDH10; CDH17
    Hepatitis C IFNA2; IKBKG; TNF; CLDN1; PPP2R1B; CLDN3; IFNA10; MAPK1; TRAF3; CLDN22
    Leukocyte transendothelial migration PIK3CG; PTK2; NCF2; PRKCB; ACTN3; JAM2; CLDN16; CLDN4; PIK3R1; CLDN5
    Tight junction CLDN7; MYH11; F11R.1; MYLPF; PPP2R2C; SPTAN1; MLLT4; ACTN2; MYL12.1; CLDN23
    Tight junction interactions CLDN7; CLDN20; CLDN3; INADL; CLDN4; CLDN16; CLDN23

    cldn7 has several biochemical functions, for example, identical protein binding, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cldn7 itself. We selected most functions cldn7 had, and list some proteins which have the same functions with cldn7. You can find most of the proteins on our site.

    Function Related Protein
    identical protein binding VWA1; ALCAMB; SLC22A1; SCHIP1; PFKL; EID3; POLG2; NIF3L1; CRYAA; AGXT2L2
    protein binding FAM161A; SP100; RASGRP3; GBA; TAF7; S100A2; NR1I2; PIM2; DPYD; C10orf81
    structural molecule activity LELP1; KRT7; FGB; COL4A3; SNTG1; KRT24; SPRR2F; KRT76; CLDN20; KRT26

    cldn7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cldn7 here. Most of them are supplied by our site. Hope this information will be useful for your research of cldn7.


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