Recombinant Human CLDN4 Protein, GST-tagged CLDN4-1443H

Recombinant Human CLDN4 Protein, GST-tagged

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Recombinant Human CLDN4 Protein, GST-tagged

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Cat.No. : CLDN4-1443H
Product Overview : Human CLDN4 full-length ORF ( AAH00671, 1 a.a. - 209 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 48.73 kDa
AA Sequence : MASMGLQVMGIALAV LGWLAVMLCCALPMW RVTAFIGSNIVTSQT IWEGLWMNCVVQSTG QMQCKVYDSLLALPQ DLQAARALVIISIIV AALGVLLSVVGGKCT NCLEDESAKAKTMIV AGVVFLLAGLMVIVP VSWTAHNIIQDFYNP LVASGQKREMGASLY VGWAASGLLLLGGGL LCCNCPPRTDKPYSA KYSAARSAAASNYV
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : CLDN4 claudin 4 [ Homo sapiens ]
Official Symbol : CLDN4
Synonyms : CLDN4; claudin 4; CPETR, CPETR1; claudin-4; Clostridium perfringens enterotoxin receptor 1; CPE R; hCPE R; WBSCR8; Williams Beuren syndrome chromosomal region 8 protein; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein; CPER; CPE-R; CPETR; CPETR1; hCPE-R;
Gene ID : 1364
mRNA Refseq : NM_001305
Protein Refseq : NP_001296
MIM : 602909
UniProt ID : O14493

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