|Official Full Name||claudin 5|
|Background||This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.|
|Synonyms||CLDN5; claudin 5; AWAL, TMVCF, transmembrane protein deleted in velocardiofacial syndrome; claudin-5; BEC1; CPETRL1; TMDVCF; transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome; AWAL; TMVCF|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
cldn5 involved in several pathways and played different roles in them. We selected most pathways cldn5 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with cldn5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cell adhesion molecules (CAMs)||CLDN16; PDCD1LG2; CD274; MHC1UXA2; CLDN17; LRRC4; CD8B1; MHC2A; NLGN2A; SELE|
|Tight junction||ACTN1; MYH13; ACTG1; CTTN; TJP1; YBX3; GNAIA; CLDNG; MYHZ2; RAB3B|
|Leukocyte transendothelial migration||GNAI1; Itgam&Itgb2; THY1; PIK3CG; RHOH; CXCR4; CLDN18; TXK; PIK3CB; PLCG2|
|Hepatitis C||IKBKB; CLDN23; CLDN4; EIF2AK1; PPP2R2A; AKT2; MAVS; OAS1A; IRF9; PPP2CA|
cldn5 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by cldn5 itself. We selected most functions cldn5 had, and list some proteins which have the same functions with cldn5. You can find most of the proteins on our site.
|molecular_function||AARSD1; CMIP; ZSWIM4; UBAP2B; PRR18; VMN1R163; UCMAB; TMEM125; SMCR8; SPANXC|
cldn5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cldn5 here. Most of them are supplied by our site. Hope this information will be useful for your research of cldn5.