|Official Full Name||claudin 2|
|Background||This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.|
|Synonyms||CLDN2; claudin 2; SP82; claudin-2; OTTHUMP00000023793; PSEC0059; UNQ705/PRO1356|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
cldn2 involved in several pathways and played different roles in them. We selected most pathways cldn2 participated on our site, such as Cell adhesion molecules (CAMs), Tight junction, Leukocyte transendothelial migration, which may be useful for your reference. Also, other proteins which involved in the same pathway with cldn2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cell adhesion molecules (CAMs)||CLDNC; ICAM3; CLDN15A; NLGN3A; NEO1A; CDH1; PTPRC; MADCAM1; PVRL1B; HLA-DRB1|
|Tight junction||PPP2R2C; CLDNF; TJAP1; CLDN14; CDC42L2; GNAI2A; MYL7; PRKCG; SHROOM3; MYH1C|
|Leukocyte transendothelial migration||CYBB; CLDN3; PLCG2; CLDN8; RAP1B; CLDN11; ACTN1; PTK2; MYL2; MAPK12|
|Hepatitis C||PIK3CB; EIF2AK3; GRB2; CLDN9; PDPK1; CLDN14; CLDN10; PPP2R2C; IFIT1; MAPK12|
cldn2 has several biochemical functions, for example, identical protein binding, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cldn2 itself. We selected most functions cldn2 had, and list some proteins which have the same functions with cldn2. You can find most of the proteins on our site.
|identical protein binding||IFIT3; ERBB2; TTC32; E2F7; ROBO2; UAP1; MRFAP1L1; TK1; PTPRG; SIRT1|
|protein binding||PSMF1; DLX4; ZFP57; AGR2; GNA13; KLHL41; FZR1; CD1d1; TOM1; BLOC1S2|
|structural molecule activity||CLDNF; CLTA; KRT23; MAP7D1B; CLTB; SPRR2E; SYNM; CLDN5B; SEPT7; CLDN9|
cldn2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cldn2 here. Most of them are supplied by our site. Hope this information will be useful for your research of cldn2.
KRT31; NOTCH2NL; KRTAP4-12; TJP1