Recombinant Human Dual Specificity Phosphatase 23, His-tagged

• Cat.No.: DUSP23-1538H
• Product Overview: Recombinant human DUSP23 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Cat. No.: DUSP23-1538H
• Description: DUSP23, also known as low molecular mass dual specificity phosphatase 3(LDP-3), belongs to the protein-tyrosine phosphatase family. This protein is a protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. This protein able to enhance activation of JNK and p38(MAPK14).
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 100mM NaCl
• Molecular Weight: 18.8kDa (170aa), confirmed by MALDI-TOF
• Purity: > 90% by SDS - PAGE
• Concentration: 1mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGVQPPNFSW VLPGRLAGLA LPRLPAHYQF LLDLGVRHLV SLTERGPPHS DSCPGLTLHR LRIPDFCPPA PDQIDRFVQI VDEANARGEA VGVHCALGFG RTGTMLACYL VKERGLAAGD AIAEIRRLRP GSIETYEQEK AVFQFYQRTK
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: DUSP23 dual specificity phosphatase 23 [ Homo sapiens ]
• Official Symbol: DUSP23
• Synonyms: DUSP23; VHZ; MOSP; LDP-3; DUSP25; FLJ20442; RP11-190A12.1; dual specificity protein phosphatase 23; VH1-like member Z; OTTHUMP00000024412; OTTHUMP00000024413; VH1-like phosphatase Z; low molecular mass dual specificity phosphatase 3; low-molecular-mass dual-specificity phosphatase 3; OTTHUMP00000033306; EC 3.1.3.16; EC 3.1.3.48; LDP3; Low molecular mass dual specificity phosphatase 3
• Gene ID: 54935
• mRNA Refseq: NM_017823
• Protein Refseq: NP_060293
• UniProt ID: Q9BVJ7
• Chromosome Location: 1q23.2
• Function: hydrolase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity