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Official Full Name dual specificity phosphatase 14
Background Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based;protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine;and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14;contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP;(mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009;(PubMed 19228121)).
Synonyms DUSP14; dual specificity phosphatase 14; dual specificity protein phosphatase 14; MKP 1 like protein tyrosine phosphatase; MKP L; MKP6; MKP-6; MAP kinase phosphatase 6; MKP-1 like protein tyrosine phosphatase; MKP-1-like protein tyrosine phosphatase; mito
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MBP
    • Myc/DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DUSP14-2511H Recombinant Human DUSP14, His & MBP tagged E.coli His/MBP
    Human DUSP14-28072TH Recombinant Human DUSP14, T7 -tagged E.coli T7
    Human DUSP14-2928H Recombinant Human DUSP14 Protein, GST-tagged Wheat Germ GST
    Human DUSP14-4928H Recombinant Human DUSP14 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human DUSP14-6781HCL Recombinant Human DUSP14 293 Cell Lysate HEK293 N/A
    Human DUSP14-853H Recombinant Human DUSP14, T7-tagged E.coli T7
    Mouse Dusp14-2683M Recombinant Mouse Dusp14 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rhesus Macaque DUSP14-1349R Recombinant Rhesus monkey DUSP14 Protein, His-tagged Mammalian Cell His
    Zebrafish DUSP14-1570Z Recombinant Zebrafish DUSP14 Mammalian Cell His

    DUSP14 involved in several pathways and played different roles in them. We selected most pathways DUSP14 participated on our site, such as Hypertrophy Model, which may be useful for your reference. Also, other proteins which involved in the same pathway with DUSP14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hypertrophy Model CYR61; ANKRD1; ZEB1B; MSTNB; ADAM10A; HBEGFB; MYOG; DUSP14; IFRD1; MSTN

    DUSP14 has several biochemical functions, for example, MAP kinase tyrosine/serine/threonine phosphatase activity, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DUSP14 itself. We selected most functions DUSP14 had, and list some proteins which have the same functions with DUSP14. You can find most of the proteins on our site.

    Function Related Protein
    MAP kinase tyrosine/serine/threonine phosphatase activity SGPP2; CTDSPL2B; SACM1LA; TENC1; PXYLP1; SACM1L; DUSP10; DUSP9; NT5DC3; PTPRQ
    poly(A) RNA binding TFAM; RPS25; REPIN1; PPHLN1; YWHAE; HEATR6; FSCN1; RPS17; BCLAF1; EEF1A1
    protein binding KDR; NMRK1; DNPEP; APOBEC3C; GLE1; AMMECR1; RPL9; RNF7; KLF13; TBCA
    protein tyrosine phosphatase activity MTMR1B; PTPN22; CDC25A; MTMR1A; DUSP28; PTP4A1; CDC14AA; CDC14AB; PTPRZ1; DUSP23A
    protein tyrosine/serine/threonine phosphatase activity SACM1L; PTEN; DUSP23A; DUSP18; CDC14C; DUSP13; DUSP4; DUSP22A; DUSP9; CTDSPL2B

    DUSP14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DUSP14 here. Most of them are supplied by our site. Hope this information will be useful for your research of DUSP14.


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