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Official Full Name dual specificity phosphatase 18
Background Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009
Synonyms DUSP18; dual specificity phosphatase 18; dual specificity protein phosphatase 18; DUSP20; LMWDSP20; Low molecular weight dual specificity phosphatase 20; LMW-DSP20; DSP18; bK963H5.1
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DUSP18-12210H Recombinant Human DUSP18, GST-tagged E.coli GST
    Human DUSP18-1923H Recombinant Human Dual Specificity Phosphatase 18, His-tagged His
    Human DUSP18-2931H Recombinant Human DUSP18 Protein, GST-tagged Wheat Germ GST
    Human DUSP18-3932H Recombinant Human DUSP18 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human DUSP18-6780HCL Recombinant Human DUSP18 293 Cell Lysate HEK293 N/A
    Mouse Dusp18-2685M Recombinant Mouse Dusp18 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat DUSP18-1974R Recombinant Rat DUSP18 Protein Mammalian Cell His
    Rhesus Macaque DUSP18-1350R Recombinant Rhesus monkey DUSP18 Protein, His-tagged Mammalian Cell His

    dusp18 involved in several pathways and played different roles in them. We selected most pathways dusp18 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with dusp18 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    dusp18 has several biochemical functions, for example, MAP kinase tyrosine/serine/threonine phosphatase activity, protein tyrosine phosphatase activity, protein tyrosine/serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by dusp18 itself. We selected most functions dusp18 had, and list some proteins which have the same functions with dusp18. You can find most of the proteins on our site.

    Function Related Protein
    MAP kinase tyrosine/serine/threonine phosphatase activity SGPP2; TENC1; SACM1LA; DUSP18; PTPRQ; DUSP6; DUSP14; DUSP8A; CTDSPL2B; PXYLP1
    protein tyrosine phosphatase activity DUSP18; MTMR4; PTPRUB; PTPN23A; MTMR7A; PTPREB; PTPN11; DUSP14; CDC25A; PTPDC1
    protein tyrosine/serine/threonine phosphatase activity NT5DC3; PTPDC1; DUSP4; DUSP26; DUSP22; DUSP15; TPTE; CDC14AB; PTP4A2A; SACM1L

    dusp18 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with dusp18 here. Most of them are supplied by our site. Hope this information will be useful for your research of dusp18.


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