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Recombinant Human PPP1R14A, His-tagged

Cat.No. : PPP1R14A-27585TH
Product Overview : Recombinant full length, Human CPI17 alpha (amino acids 1-147) with N terminal His tag; 167 amino acids, with a predicted MWt 18 kDa including tag.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Protein length : 147 amino acids
Conjugation : HIS
Molecular Weight : 18.000kDa inclusive of tags
Source : E. coli
Tissue specificity : Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : pH: 8.00Constituents:0.32% Tris HCl, 0.06% EDTA, 0.02% DTT, 10% Glycerol
Storage : Please see Notes section
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MAAQRLGKRV LSKLQSPSRA RGPGGSPGGL QKRHARVTVK YDRRELQRRL DVEKWIDGRL EELYRGMEAD MPDEINIDEL LELESEEERS RKIQGLLKSC GKPVEDFIQE LLAKLQGLHR QPGLRQPSPS HDGSLSPLQD RARTAHP
Sequence Similarities : Belongs to the PP1 inhibitor family.
Gene Name : PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A [ Homo sapiens ]
Official Symbol : PPP1R14A
Synonyms : PPP1R14A; protein phosphatase 1, regulatory (inhibitor) subunit 14A; PPP1INL; protein phosphatase 1 regulatory subunit 14A; 17 kDa PKC potentiated inhibitory protein of PP1; 17 KDa protein; CPI 17; PKC potentiated inhibitory protein of PP1;
Gene ID : 94274
mRNA Refseq : NM_001243947
Protein Refseq : NP_001230876
MIM : 608153
Uniprot ID : Q96A00
Chromosome Location : 19q13.1
Pathway : Vascular smooth muscle contraction, organism-specific biosystem; Vascular smooth muscle contraction, conserved biosystem;
Function : protein phosphatase inhibitor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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