"PPP1R14A" Related Products

Recombinant Human PPP1R14A, His-tagged

Cat.No.: PPP1R14A-27586TH
Product Overview: Recombinant Full Length human CPI17 alpha with His tag; 167 aa, 18kDa.
Description: The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Conjugation: HIS
Source: E. coli
Tissue specificity: Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris, 2mM EDTA, 1mM DTT, pH 8.0
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAAQRLGKRV LSKLQSPSRA RGPGGSPGGL QKRHARVTVK YDRRELQRRL DVEKWIDGRL EELYRGMEAD MPDEINIDEL LELESEEERS RKIQGLLKSCGKPVEDFIQE LLAKLQGLHR QPGLRQPSPS HDGSLSPLQD RARTAHP
Sequence Similarities: Belongs to the PP1 inhibitor family.
Gene Name: PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A [ Homo sapiens ]
Official Symbol: PPP1R14A
Synonyms: PPP1R14A; protein phosphatase 1, regulatory (inhibitor) subunit 14A; PPP1INL; protein phosphatase 1 regulatory subunit 14A; 17 kDa PKC potentiated inhibitory protein of PP1; 17 KDa protein; CPI 17; PKC potentiated inhibitory protein of PP1;
Gene ID: 94274
mRNA Refseq: NM_001243947
Protein Refseq: NP_001230876
MIM: 608153
Uniprot ID: Q96A00
Chromosome Location: 19q13.1
Pathway: Vascular smooth muscle contraction, organism-specific biosystem; Vascular smooth muscle contraction, conserved biosystem;
Function: protein phosphatase inhibitor activity;

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