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GMP Recombinant Human GDF11 Protein

Cat.No.: GDF11-137HG
Product Overview: Recombinant Human GDF11, Asn299-Ser407, was produced in E. coli using non-animal reagents in an animal-free facility under cGMP guidelines.
Source: E. coli
Species: Human
Form: Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Bio-activity: Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340.
Molecular Mass: Predicted Molecular Mass: 12.6 (monomer) kDa
SDS-PAGE: 12 kDa, reducing conditions
N-terminal Sequence Analysis: Met-Asn299-Leu-Gly-Leu-Asp-(Cys)-Asp-Glu-His
Endotoxin: <0.01 EU per 1 μg of the protein by the LAL method.
Purity: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Storage: Avoid repeated freeze-thaw cycles.
12 months, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution: Reconstitute at 100 μg/mL in 4 mM HCl.
Quality Statement: Our GMP proteins are produced according to relevant sections of the following documents: WHO TRS, No. 822, 1992 Annex 1, Good Manufacturing Practices for Biological Products; USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and USP Chapter 92, Growth Factors and Cytokines Used in Cell Therapy Manufacturing.
Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.
Gene Name: GDF11 growth differentiation factor 11 [ Homo sapiens ]
Official Symbol: GDF11
Synonyms: GDF11; growth differentiation factor 11; growth/differentiation factor 11; BMP 11; GDF-11; bone morphogenetic protein 11; BMP11; BMP-11;
Gene ID: 10220
mRNA Refseq: NM_005811
Protein Refseq: NP_005802
MIM: 603936
UniProt ID: O95390

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