gdf9

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gdf9

Official Full Name growth differentiation factor 9
Background Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Growth differentiation factor-9 (GDF9) is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9 is a member of the transforming growth factor-beta superfamily.
Synonyms GDF9; growth differentiation factor 9; growth/differentiation factor 9; GDF-9
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GDF9-223H Recombinant Human Growth Differentiation Factor 9, His-tagged E.coli His
    Human GDF9-245H Recombinant Human Growth Differentiation Factor 9 E.coli N/A
    Human GDF9-4830H Recombinant Human GDF9 Protein, GST-tagged Wheat Germ GST
    Human GDF9-5966HCL Recombinant Human GDF9 293 Cell Lysate HEK293 N/A
    Human GDF9-999H Recombinant Human GDF9 HEK293 N/A
    Mouse Gdf9-180M Recombinant Mouse Gdf9 CHO N/A
    Mouse GDF9-6290M Recombinant Mouse GDF9 Protein Mammalian Cell His
    Mouse Gdf9-643M Recombinant Mouse Gdf9 Protein, His-tagged E.coli His
    Mouse Gdf9-726M Recombinant Mouse Growth Differentiation Factor 9 CHO N/A
    Rat Gdf9-644R Recombinant Rat Gdf9 Protein, His-tagged E.coli His
    Chicken GDF9-7111C Recombinant Chicken GDF9 Mammalian Cell His
    Zebrafish GDF9-2037Z Recombinant Zebrafish GDF9 Mammalian Cell His

    gdf9 involved in several pathways and played different roles in them. We selected most pathways gdf9 participated on our site, such as Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with gdf9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ovarian steroidogenesis INS; BMP15; LHCGR; FSHB; BMP6; GNAS; INS1; PLA2G4C; IGF1; CYP2J6

    gdf9 has several biochemical functions, for example, cytokine activity, growth factor activity, transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by gdf9 itself. We selected most functions gdf9 had, and list some proteins which have the same functions with gdf9. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity NAMPT; KITLG; Ifna15; IFNA17; AREG; GREM1; IL12BA; IL1B; GDF10B; SPAW
    growth factor activity GFER; TIMP1; MSTN; CXCL12; FGF4; PDGFAA; NRG4; IL10; IGF2A; FGF8B
    transforming growth factor beta receptor binding GDF15; GDF6; TGFBRAP1; GDF9; SMAD3; LFT2; BMP2; TGFB1A; BMP3; NODAL

    gdf9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with gdf9 here. Most of them are supplied by our site. Hope this information will be useful for your research of gdf9.

    TK1; SMN1; PSMD11; DLEU1; KDM1A; PRKRA; GADD45G; S100A8; TDGF1; ANXA7; SAT1; CDKN1A; CDKN2C; SERPINB9; DNM2; RAB27A; FOXG1; SNRPG

    Pan, B; Toms, D; et al. MicroRNA-378 regulates oocyte maturation via the suppression of aromatase in porcine cumulus cells. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 308:E525-E534(2015).
    Nakamura, T; Iwase, A; et al. CYP51A1 Induced by Growth Differentiation Factor 9 and Follicle-Stimulating Hormone in Granulosa Cells Is a Possible Predictor for Unfertilization. REPRODUCTIVE SCIENCES 22:377-384(2015).

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