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  • Official Full Name

    growth differentiation factor 9

  • Overview

    Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Growth differentiation factor-9 (GDF9) is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9 is a member of the transforming growth factor-beta superfamily.
  • Synonyms

    GDF9; growth differentiation factor 9; growth/differentiation factor 9; GDF-9;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • CHO
  • E. coli
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GDF9-999H Active Recombinant Human GDF9 HEK293 N/A Gly320-Arg454
Human GDF9-245H Recombinant Human Growth Differentiation Factor 9 E.coli N/A
Human GDF9-223H Recombinant Human Growth Differentiation Factor 9, His-tagged E.coli His
Human GDF9-5966HCL Recombinant Human GDF9 293 Cell Lysate HEK293 N/A
Human GDF9-2953H Recombinant Human GDF9 protein, GST-tagged E.coli GST 320-454aa
Human GDF9-3341H Recombinant Human GDF9 Protein (Gly320-Arg454), His tagged E.coli His Gly320-Arg454
Human GDF9-4830H Recombinant Human GDF9 Protein, GST-tagged Wheat Germ GST
Human GDF9-053H Active Recombinant Human GDF9 Protein E. coli
Human GDF9-5241HF Recombinant Full Length Human GDF9 Protein, GST-tagged In Vitro Cell Free System GST 454 amino acids
Mouse Gdf9-180M Active Recombinant Mouse Gdf9 CHO N/A
Mouse Gdf9-726M Active Recombinant Mouse Growth Differentiation Factor 9 CHO N/A
Mouse Gdf9-643M Recombinant Mouse Gdf9 Protein, His-tagged E.coli His Gly307~Arg441
Mouse GDF9-6290M Recombinant Mouse GDF9 Protein Mammalian Cell His
Mouse GDF9-3523M Recombinant Mouse GDF9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GDF9-3523M-B Recombinant Mouse GDF9 Protein Pre-coupled Magnetic Beads HEK293
Rat Gdf9-644R Recombinant Rat Gdf9 Protein, His-tagged E.coli His Arg306~Arg440
Zebrafish GDF9-2037Z Recombinant Zebrafish GDF9 Mammalian Cell His
Chicken GDF9-7111C Recombinant Chicken GDF9 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GDF9 Related Articles

GDF9 involved in several pathways and played different roles in them. We selected most pathways GDF9 participated on our site, such as Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ovarian steroidogenesisIGF1;PLA2G4F;HSD3B1;LHCGR;BMP6;PLA2G4C;AKR1C3;BMP15;HSD3B6

GDF9 has several biochemical functions, for example, cytokine activity, growth factor activity, transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF9 itself. We selected most functions GDF9 had, and list some proteins which have the same functions with GDF9. You can find most of the proteins on our site.

Function Related Protein
cytokine activityGM13289;Il1f8;IFNA10;SPAW;IL16;IL5;IL21;Flt3l;IL17C
growth factor activityFGF13;BMP16;CSF3;THBS4;BMP8B;IL11;PDGFA;FGF12;GMFB
transforming growth factor beta receptor bindingMSTN;BMP15;INHBB;GDF6B;SMAD2;BMP8A;GDF10;GDF5;BMP2B

GDF9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDF9 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDF9.


Pan, B; Toms, D; et al. MicroRNA-378 regulates oocyte maturation via the suppression of aromatase in porcine cumulus cells. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 308:E525-E534(2015).
Nakamura, T; Iwase, A; et al. CYP51A1 Induced by Growth Differentiation Factor 9 and Follicle-Stimulating Hormone in Granulosa Cells Is a Possible Predictor for Unfertilization. REPRODUCTIVE SCIENCES 22:377-384(2015).
  • Q&As
  • Reviews

Q&As (7)

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How does GDF9 influence the proliferation and differentiation of granulosa cells in the ovary? 03/26/2021

GDF9 stimulates granulosa cell proliferation and differentiation, essential for healthy ovarian function.

What are the mechanisms by which GDF9 modulates intra-ovarian signaling pathways? 10/12/2020

GDF9 interacts with intra-ovarian signaling pathways, coordinating follicle development and ovulation.

How do alterations in GDF9 expression or function affect embryonic development and early pregnancy? 09/17/2020

Changes in GDF9 expression impact embryonic development and the success of early pregnancy stages.

What role does GDF9 play in fertility and reproductive outcomes in females? 11/28/2019

GDF9 significantly impacts female fertility, affecting egg quality and reproductive potential.

What is the impact of GDF9 mutations on the pathogenesis of ovarian dysfunctions and disorders? 04/28/2019

Mutations in GDF9 can lead to ovarian disorders, impacting follicle development and female fertility.

How does GDF9 regulate ovarian follicle development and oocyte maturation? 04/22/2019

GDF9 is crucial for ovarian follicle growth and oocyte maturation, influencing female fertility.

How does GDF9 contribute to the regulation of steroidogenesis in ovarian cells? 09/30/2018

GDF9 regulates steroid hormone production in ovarian cells, influencing reproductive hormone balance.

Customer Reviews (3)

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    Expertise in peptide synthesis, accelerates our peptide-related projects.


      Swift protein quantification, improves data reliability in our experiments.


        Outstanding protein-protein interaction studies, boost our research efforts.

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