|Official Full Name||growth differentiation factor 11|
|Background||The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.|
|Synonyms||GDF11; growth differentiation factor 11; growth/differentiation factor 11; BMP 11; GDF-11; bone morphogenetic protein 11; BMP11; BMP-11|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GDF11 involved in several pathways and played different roles in them. We selected most pathways GDF11 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
GDF11 has several biochemical functions, for example, cytokine activity, growth factor activity, transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF11 itself. We selected most functions GDF11 had, and list some proteins which have the same functions with GDF11. You can find most of the proteins on our site.
|cytokine activity||Kitl; IL1A; SPP1; IL17F; ADIPOQ; FAM3C; Ifna11; BMP7A; CMTM2B; IL17A/F1|
|growth factor activity||TGFB2; OSGIN1; FGF12A; BMP3; KLK1B3; NRTN; GDF2; TDGF1; NTF3; GPR19|
|transforming growth factor beta receptor binding||BMP10; TGFBR3; INHBE; GDF9; LEFTY1; LRG1; SMAD3; BMP15; GDF15; INHBA|
GDF11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDF11 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDF11.
ACVR2B; Acvr1b; Tgfbr1; Acvr1c; WFIKKN2; WFIKKN1