GDF3
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Official Full Name
growth differentiation factor 3
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Overview
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. [provided by RefSeq, Jul 2008] -
Synonyms
GDF3; growth differentiation factor 3; KFS3; MCOP7; MCOPCB6; growth/differentiation factor 3; GDF-3;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- CHO
- E. coli
- E.coli
- HEK293
- Human
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- GDF3 Related Articles
- GDF3 Related Gene Family
- GDF3 Related Research Area
GDF3 involved in several pathways and played different roles in them. We selected most pathways GDF3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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GDF3 has several biochemical functions, for example, cytokine activity, growth factor activity, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF3 itself. We selected most functions GDF3 had, and list some proteins which have the same functions with GDF3. You can find most of the proteins on our site.
Function | Related Protein |
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cytokine activity | GDF6B;FGF2;IL16;IFNA4;IFNA10;IL36G;BMP10;IL1A;Ifnz |
growth factor activity | CSPG5;FGF14;INHBC;FGF6;PDGFAA;VEGFC;IL6;CSF1B;MDKA |
protein kinase binding | ADIPOR1;NBEA;NPR1;SREBF1;CDKN2D;CD3E;CACNB2;FGF19;GPRC5B |
transforming growth factor beta receptor binding | GDF7;TGFBR3;LFT1;GDF5;INHBB;INHA;LEFTY1;LFT2;INHBAA |
GDF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDF3.
- Q&As
- Reviews
Q&As (5)
Ask a questionGDF3 signaling may crosstalk with Wnt, Notch, and other signaling pathways, modulating their activities and integrating them into a complex regulatory network during development.
GDF3 is implicated in organogenesis, influencing the development of various tissues and organs, including the heart, nervous system, and mesoderm-derived structures.
Post-translational modifications, such as glycosylation and phosphorylation, play roles in regulating GDF3 activity, influencing its stability, secretion, and interaction with receptors.
GDF3 activates the SMAD signaling pathway, influencing cellular processes such as proliferation, differentiation, and apoptosis, especially during early embryonic development.
GDF3 is essential for germ cell development and contributes to the establishment of primordial germ cells, influencing fertility and reproductive success.
Customer Reviews (3)
Write a reviewQuick service response—customer support helped us navigate product options.
Speedy delivery! Received this product in excellent condition, ready to use.
This protein's consistent performance is a testament to its quality.
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