GDF3

  • Official Full Name

    growth differentiation factor 3

  • Overview

    The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. [provided by RefSeq, Jul 2008]
  • Synonyms

    GDF3; growth differentiation factor 3; KFS3; MCOP7; MCOPCB6; growth/differentiation factor 3; GDF-3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • CHO
  • E. coli
  • E.coli
  • HEK293
  • Human
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GDF3-02H Active Recombinant Human GDF3 E.coli N/A
Human GDF3-246H Recombinant Human GDF3 CHO N/A
Human GDF3-584H Recombinant Human Growth Differentiation Factor 3 Human His
Human GDF3-5969HCL Recombinant Human GDF3 293 Cell Lysate HEK293 N/A
Human GDF3-3584H Recombinant Human GDF3 Protein (Ala251-Gly364), His tagged E.coli His
Human GDF3-271H Recombinant Human GDF3 Protein, His-tagged E.coli His
Human GDF3-5238HF Recombinant Full Length Human GDF3 Protein, GST-tagged In Vitro Cell Free System GST
Human GDF3-4825H Recombinant Human GDF3 Protein, GST-tagged Wheat Germ GST
Human GDF3-3659H Recombinant Human GDF3 protein, His-tagged E.coli His
Human GDF3-048H Active Recombinant Human GDF3 Protein E. coli
Mouse Gdf3-718M Active Recombinant Mouse Growth Differentiation Factor 3 E.coli N/A
Mouse GDF3-6287M Recombinant Mouse GDF3 Protein Mammalian Cell His
Mouse GDF3-3520M Recombinant Mouse GDF3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GDF3-3520M-B Recombinant Mouse GDF3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Gdf3-272M Recombinant Mouse Gdf3 Protein, His-tagged E.coli His
Rat Gdf3-273R Recombinant Rat Gdf3 Protein, His-tagged E.coli His
Zebrafish GDF3-8587Z Recombinant Zebrafish GDF3 Mammalian Cell His
Chicken GDF3-6764C Recombinant Chicken GDF3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GDF3 Related Articles
  • GDF3 Related Gene Family
  • GDF3 Related Research Area

GDF3 involved in several pathways and played different roles in them. We selected most pathways GDF3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

GDF3 has several biochemical functions, for example, cytokine activity, growth factor activity, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF3 itself. We selected most functions GDF3 had, and list some proteins which have the same functions with GDF3. You can find most of the proteins on our site.

Function Related Protein
cytokine activityINHBAA;TNF;BMP7;MSTNB;GPI1;TGFB3;CMTM2;Il23a; Il12b;Ccl12
growth factor activityBMP6;GRN;FGF1A;FGF10A;TIMP1;INHBA;FBRS;EFEMP1;IL5
protein kinase bindingNPR1;CCNE1;DUSP3;USP37;FBXO7;PTPRR;TPRKB;CDC25A;TRIM5
transforming growth factor beta receptor bindingGDF10;BMP8A;TGFB1A;BMP8B;TGFB2;BMP7;SMAD3;LRG1;GDF11

GDF3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDF3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDF3.

Adewumi, O; Aflatoonian, B; et al. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. NATURE BIOTECHNOLOGY 25:803-816(2007).
TGF
  • Q&As
  • Reviews

Q&As (5)

Ask a question
Explain the crosstalk between GDF3 signaling and other cellular pathways. 04/08/2022

GDF3 signaling may crosstalk with Wnt, Notch, and other signaling pathways, modulating their activities and integrating them into a complex regulatory network during development.

Discuss the role of GDF3 in organogenesis and tissue development during embryogenesis. 02/18/2021

GDF3 is implicated in organogenesis, influencing the development of various tissues and organs, including the heart, nervous system, and mesoderm-derived structures.

Explain the post-translational modifications involved in regulating GDF3 activity. 05/27/2020

Post-translational modifications, such as glycosylation and phosphorylation, play roles in regulating GDF3 activity, influencing its stability, secretion, and interaction with receptors.

What are the signaling pathways activated by GDF3, and how do they contribute to cellular processes? 09/11/2019

GDF3 activates the SMAD signaling pathway, influencing cellular processes such as proliferation, differentiation, and apoptosis, especially during early embryonic development.

How is GDF3 involved in the regulation of germ cell development and fertility? 12/15/2018

GDF3 is essential for germ cell development and contributes to the establishment of primordial germ cells, influencing fertility and reproductive success.

Customer Reviews (3)

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Reviews
01/14/2022

    Quick service response‚ÄĒcustomer support helped us navigate product options.

    06/21/2019

      Speedy delivery! Received this product in excellent condition, ready to use.

      12/07/2018

        This protein's consistent performance is a testament to its quality.

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