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Official Full Name growth differentiation factor 1
Background This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of;proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein;containing seven conserved cysteine residues. The members of this family are regulators of cell growth and;differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein is involved in the;establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This;protein is transcribed from a bicistronic mRNA that also encodes the longevity assurance gene.
Synonyms GDF1; growth differentiation factor 1; embryonic growth/differentiation factor 1; GDF-1; DORV; DTGA3
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO
    • E.coli
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GDF1-4817H Recombinant Human GDF1 Protein, GST-tagged Wheat Germ GST
    Human GDF1-715H Recombinant Human GDF1 CHO N/A
    Human GDF1-717H Recombinant Human Growth Differentiation Factor 1 CHO N/A
    Mouse Gdf1-269M Recombinant Mouse Gdf1 Protein, His-tagged E.coli His
    Rat Gdf1-270R Recombinant Rat Gdf1 Protein, His-tagged E.coli His

    gdf1 involved in several pathways and played different roles in them. We selected most pathways gdf1 participated on our site, such as Developmental Biology, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with gdf1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Developmental Biology DUSP5; NRG3; STX1B; LGI2; SPNA1; ACTR3; EPHB4A; CNTN1; ARHGEF28; EFNA5
    Metabolism AZIN2; GYG1B; SLC5A9; AZIN1; GYG1A; GC; PDK2; CEPT1A; DTYMK; ATP5L
    Metabolism of lipids and lipoproteins ALOX5B.2; ACOT8; ACOT7; ACOT12; CDIPT; NEU3; APOEA; CYP4F22; GDF1; SLCO1B1
    Signaling by NODAL LEFTY1; DRAP1; ACVR1C; CFC1; PCSK6; GDF1; FOXH1; TDGF1
    Sphingolipid de novo biosynthesis CERS3B; OSBP; CERS5; PPM1L; VAPB; GDF1; COL4A3BP; SGMS2; PPM1LB; FA2H
    Sphingolipid metabolism LASS5; CERS2A; NEU3.5; SMPD2A; CERS4A; ASAH1; OSBP; CERK; SPTLC3; GBA

    gdf1 has several biochemical functions, for example, cytokine activity, growth factor activity, transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by gdf1 itself. We selected most functions gdf1 had, and list some proteins which have the same functions with gdf1. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity IL21; GM13288; FASLG; BMP3; GDF10B; CD40LG; Gm13290; MIF; IFNPHI3; INHBC
    growth factor activity RABEP2; ANGPTL3; IL5; FGF11A; VEGFAA; HDGFRP3; VEGFC; TGFB2; FGF2; MDKB
    transforming growth factor beta receptor binding BMP8A; GDF10B; USP15; MSTNB; GDF6B; INHBB; INHBC; BMP3; FKBP1A; INHBAA

    gdf1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with gdf1 here. Most of them are supplied by our site. Hope this information will be useful for your research of gdf1.


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