GDF7

  • Official Full Name

    growth differentiation factor 7

  • Overview

    This gene encodes a member of the bone morphogenetic protein (BMP) family. BMPs belong to the transforming growth factor-beta superfamily of secreted signalling molecules that regulate diverse processes in growth, repair and embryonic development. In mouse, this gene functions as an inductive signal from the roof plate required for the specification of neuronal identity in the dorsal spinal cord.
  • Synonyms

    GDF7; growth differentiation factor 7; growth/differentiation factor 7; BMP12; bone morphogenetic protein 12; GDF-7; GDF7_HUMAN; OTTHUMP00000115986;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • His(C
  • ter)
  • N/A
  • N
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GDF7 Related Articles
  • GDF7 Related Gene Family

GDF7 involved in several pathways and played different roles in them. We selected most pathways GDF7 participated on our site, such as Hippo signaling pathway, TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Hippo signaling pathwayBMPR2;BMPR1A;WNT1;PPP1CB;CRB2;PPP2R1B;GSK3B;SMAD2;ACTB
TGF-beta signaling pathwayID2A;BMPR1B;FSTA;PPP2R1A;BAMBI;AMHR2;BMPR2A;RHOA;BMPR1AA

GDF7 has several biochemical functions, for example, cytokine activity, growth factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF7 itself. We selected most functions GDF7 had, and list some proteins which have the same functions with GDF7. You can find most of the proteins on our site.

Function Related Protein
cytokine activityOSTN;GDF10B;IL29;NODAL;IL17A/F2;IL17F;RNF207B;VEGFA;GM13278
growth factor activityFGF5;NRTN;TFF1;CLEC11A;PDGFAA;PDGFD;GH1;AGT;RABEP2
protein bindingFAM131B;SLC4A1A;KCNG3;ANKRD27;TUBA3C;LMNA;CCDC130;MARVELD2;EIF3M
protein homodimerization activityAP1S2;Defa-rs7;SDS;EIF2AK1;ZNF174;CAMK2D;LRRK2;TFAP4;IZUMO3
transforming growth factor beta receptor bindingGDF3;BMP8B;BMP7;GDF15;GDF6B;TGFBR3;GDF11;TGFB1A;INHBAB

GDF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDF7.

Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).
Wendroth, SM; Mentrikoski, MJ; et al. GATA3 expression in morphologic subtypes of breast carcinoma: a comparison with gross cystic disease fluid protein 15 and mammaglobin. ANNALS OF DIAGNOSTIC PATHOLOGY 19:6-9(2015).
TGF
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