GDF10

  • Official Full Name

    growth differentiation factor 10

  • Overview

    The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis.
  • Synonyms

    GDF10; growth differentiation factor 10; bone morphogenetic protein 3B; BMP 3b; BIP; GDF-10; bone-inducing protein; BMP3B; BMP-3b;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • hFc
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GDF10-27683TH Recombinant Human GDF10 protein E.coli N/A
Human GDF10-474H Recombinant Human Growth Differentiation Factor 10 E.coli N/A
Human GDF10-4818H Recombinant Human GDF10 Protein, GST-tagged Wheat Germ GST
Human GDF10-284H Recombinant Human GDF10 Protein, His-tagged E.coli His
Human GDF10-5230HF Recombinant Full Length Human GDF10 Protein, GST-tagged In Vitro Cell Free System GST
Human GDF10-436G Recombinant Human GDF10 Protein (111 aa) E.coli
Human GDF10-3317H Recombinant Human GDF10 Protein (369-478), His tagged E.coli His
Human GDF10-3319H Recombinant Human GDF10 Protein (Gln369-Arg478), N-His tagged E.coli N-His
Mouse Gdf10-4014M Recombinant Mouse Gdf10 protein, hFc-tagged HEK293 hFc
Mouse GDF10-2101MCL Recombinant Mouse GDF10 cell lysate Human Cell N/A
Mouse Gdf10-286M Recombinant Mouse Gdf10 Protein, His-tagged E.coli His
Rat GDF10-2501R Recombinant Rat GDF10 Protein Mammalian Cell His
Rat GDF10-2157R Recombinant Rat GDF10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GDF10-2157R-B Recombinant Rat GDF10 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GDF10 Related Articles
  • GDF10 Related Gene Family
  • GDF10 Related Research Area

GDF10 involved in several pathways and played different roles in them. We selected most pathways GDF10 participated on our site, such as Adipogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
AdipogenesisNR2F1A;KCNA3;CELF1;NR2F1;BMP1;BSCL2;GTF3AA;EPAS1B;GATA2

GDF10 has several biochemical functions, for example, cytokine activity, growth factor activity, transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF10 itself. We selected most functions GDF10 had, and list some proteins which have the same functions with GDF10. You can find most of the proteins on our site.

Function Related Protein
cytokine activityWNT1;IFNA8;TNFB;SP100;GDF11;LTB;FAM3B;Ifna11;AREG
growth factor activityFGF24;Artn;BMP6;FGF18A;GDF5;LACRT;F2;RABEP1;MANF
transforming growth factor beta receptor bindingTGFBRAP1;BMP15;GDF2;GDF15;INHBAA;GDF11;NODAL;SMURF2;GDF10

GDF10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDF10 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDF10.

IGHA1

Liu, QW; Chen, JR; et al. Identification of stage-specific markers during differentiation of hair cells from mouse inner ear stem cells or progenitor cells in vitro. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 60:99-111(2015).
Monestier, O; Servin, B; et al. Evolutionary Origin of Bone Morphogenetic Protein 15 and Growth and Differentiation Factor 9 and Differential Selective Pressure Between Mono- and Polyovulating Species. BIOLOGY OF REPRODUCTION 91:-(2014).
TGF
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