Recombinant Human C1orf56 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: C1orf56-929H
• Product Overview: C1orf56 MS Standard C13 and N15-labeled recombinant protein (NP_060330) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene is a proto-oncogene whose promoter is methylated by DNA methyltransferase 3B (DNMT3B), which represses the proto-oncogene. However, a catalytically inactive isoform of DNMT3B is overexpressed in lymphomas, leading to hypomethylation of the proto-oncogene's promoter and derepression of the proto-oncogene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 36.8 kDa
• AA Sequence: MVPAAGALLWVLLLNLGPRAAGAQG LTQTPTEMQRVSLRFGGPMTRSYRS TARTGLPRKTRIILEDENDAMADAD RLAGPAAAELLAATVSTGFSRSSAI NEEDGSSEEGVVINAGKDSTSRELP SATPNTAGSSSTRFIANSQEPEIRL TSSLPRSPGRSTEDLPGSQATLSQW STPGSTPSRWPSPSPTAMPSPEDLR LVLMPWGPWHCHCKSGTMSRSRSGK LHGLSGRLRVGALSQLRTEHKPCTY QQCPCNRLREECPLDTSLCTDTNCA SQSTTSTRTTTTPFPTIHLRSSPSL PPASPCPALAFWKRVRIGLEDIWNS LSSVFTEMQPIDRNQRTRTRPLEQK LISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: C1orf56 chromosome 1 open reading frame 56 [ Homo sapiens (human) ]
• Official Symbol: C1orf56
• Synonyms: C1ORF56; chromosome 1 open reading frame 56; uncharacterized protein C1orf56; FLJ20519; RP11-316M1.9
• Gene ID: 54964
• mRNA Refseq: NM_017860
• Protein Refseq: NP_060330
• UniProt ID: Q9BUN1