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Official Full Name chromosome 10 open reading frame 2
Synonyms C10ORF2;chromosome 10 open reading frame 2;infantile onset spinocerebellar ataxia (autosomal recessive), IOSCA;twinkle protein, mitochondrial;FLJ21832;PEO;PEO1;twinkle;TWINKLE;TWINL;ataxin 8;mitochondrial twinkle protein;T7-like mitochondrial DNA helicase;progressive external ophthalmoplegia 1 protein;T7 gp4-like protein with intramitochondrial nucleoid localization;SCA8;ATXN8;IOSCA;PEOA3;SANDO;MTDPS7;
    • Species :
    • Human
    • Source :
    • HEK293
    • Tag :
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human C10orf2-8371HCL Recombinant Human C10orf2 293 Cell Lysate HEK293 N/A

    c10orf2 involved in several pathways and played different roles in them. We selected most pathways c10orf2 participated on our site, such as Mitochondrial biogenesis, Organelle biogenesis and maintenance, Transcriptional activation of mitochondrial biogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with c10orf2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Mitochondrial biogenesis PPARGC1B; ESRRA; POLRMT; PPRC1; GABPA; POLG2; TFB2M; MTERF; C10orf2; TFB1M
    Organelle biogenesis and maintenance MRPS36; CC2D2A; MTRF1L; NPHP3; TTC30B; PKD2; GABPA; MRPL50; CCDC123; BBS9
    Transcriptional activation of mitochondrial biogenesis C10orf2; PPRC1; GABPB1; TFB1M; GABPA; MTERF; POLRMT; POLG2

    c10orf2 has several biochemical functions, for example, 5-3 DNA helicase activity, ATP binding, protease binding. Some of the functions are cooperated with other proteins, some of the functions could acted by c10orf2 itself. We selected most functions c10orf2 had, and list some proteins which have the same functions with c10orf2. You can find most of the proteins on our site.

    Function Related Protein
    5-3 DNA helicase activity C10orf2; DNA2; PEO1; ERCC2
    ATP binding CCT5; Abcb1b; MAP2K4A; ACSM5; ACTB2; VARS2; RPS6KB2; SRPK1B; ABCB3L1; CAD
    protease binding FAP; NDUFS7; SERPINB4; THAP5; FURIN; CST3; ITGAV; IL1R1; SERPINA1D; BCL2
    single-stranded DNA binding SSBP3A; PURB; RBMS1; CSDA; NCL; LRPPRC; RPA2; RPA4; NABP2; NABP1

    c10orf2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with c10orf2 here. Most of them are supplied by our site. Hope this information will be useful for your research of c10orf2.


    Muneta, Y; Kikuma, R; et al. Molecular cloning, chromosomal location, and biological activity of porcine interleukin-21. JOURNAL OF VETERINARY MEDICAL SCIENCE 66:269-275(2004).
    Xie, JP; Cai, T; et al. The zinc-finger transcription factor INSM1 is expressed during embryo development and interacts with the cbl-associated protein. GENOMICS 80:54-61(2002).

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