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C8B

  • Official Full Name

    complement component 8, beta polypeptide

  • Overview

    C8 beta is one of the three subunits that comprise the component 8 (C8) of the complement system. C8 participates in the formation of Membrane Attack Complex that results in the lysis of cells. Patients with C8B deficiency are prone to bacteria infection.
  • Synonyms

    C8B; complement component 8, beta polypeptide; complement component C8 beta chain; complement component 8 subunit beta; MGC163447;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • His|T7
  • MYC
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human C8B-6786H Recombinant Human C8B protein, His & T7-tagged E.coli His/T7 Cys162~His504 (Accession # P07358)
Human C8B-7955HCL Recombinant Human C8B 293 Cell Lysate HEK293 N/A
Human C8B-617H Recombinant Human C8B protein, His&Myc-tagged E.coli His&Myc 55-591aa
Human C8B-618H Recombinant Human C8B protein, His-tagged E.coli His 55-591aa
Human C8B-0617H Recombinant Human C8B Protein (Cys162-His504), N-His-tagged E.coli N-His Cys162-His504
Human C8B-1903HFL Recombinant Full Length Human C8B Protein, C-Flag-tagged Mammalian cells Flag
Human C8B-476H Recombinant Human C8B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human C8B-476H-B Recombinant Human C8B Protein Pre-coupled Magnetic Beads HEK293
Mouse C8b-6787M Recombinant Mouse C8b protein, His & T7-tagged E.coli His/T7 Cys161~Arg503 (Accession # Q8BH35)
Mouse C8b-469M Recombinant Mouse C8b Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat C8b-6788R Recombinant Rat C8b protein, His & T7-tagged E.coli His/T7 Cys161~Arg503 (Accession # P55314)
Rat C8B-1055R Recombinant Rat C8B Protein Mammalian Cell His
Rat C8B-713R Recombinant Rat C8B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat C8B-713R-B Recombinant Rat C8B Protein Pre-coupled Magnetic Beads HEK293
Zebrafish C8B-8192Z Recombinant Zebrafish C8B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • C8B Related Research Area

C8B involved in several pathways and played different roles in them. We selected most pathways C8B participated on our site, such as Complement and coagulation cascades, Prion diseases, Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with C8B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Complement and coagulation cascadesSERPINF2;CFB;F2R;C7;F9;C8A;SERPINC1;C4A;C6
Prion diseasesPRKACB;BAX;HSPA1A;CCL5;Hc;C6;IL1B;CASP12;NCAM2
AmoebiasisItgam&Itgb2;LAMB4;C9;SERPINB1;IL12B;TLR2;GNAL;ARG1;PIK3R1
Systemic lupus erythematosusHIST1H2AN;HIST1H2AH;HIST1H3H;HLA-DQA1;HLA-DRA;GRIN2B;HIST1H2BM;H2AFV;C2

C8B has several biochemical functions, for example, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C8B itself. We selected most functions C8B had, and list some proteins which have the same functions with C8B. You can find most of the proteins on our site.

Function Related Protein
protein complex bindingDRD1A;ATM;IST1;MYC;LRP2;RBX1;PTPRF;NASP;HNF1B

C8B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C8B here. Most of them are supplied by our site. Hope this information will be useful for your research of C8B.

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