C4B
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Official Full Name
complement component 4B (Chido blood group)
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Overview
C4b binding protein (C4BP) regulates complement activation of the classical and lectin pathways. It binds to C4b and accelerates the dissociation of C2a from the C3/C5 convertase C4b,C2a. -
Synonyms
C4b Binding Protein; C4B; complement component 4B (Chido blood group); complement component 4B (Chido blood group);
- Recombinant Proteins
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- Human Plasma
- Human serum
- Mammalian Cell
- Normal human serum (shown by certified tests to be negative for HBsAg and for antibodies to HCV, HIV-1 and HIV-II)
- Wheat Germ
- Yeast
- GST
- His
- His (Fc)
- Avi
- His|T7
- SUMO
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | C4B-26130TH | Recombinant Human C4B | Wheat Germ | N/A | 100 amino acids |
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| Human | C4B-27789TH | Recombinant Human C4B | Wheat Germ | N/A | 100 amino acids |
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| Human | C4B-254H | Recombinant Human C4B protein, His/T7-tagged | E.coli | His/T7 | ||
| Human | C4B-0051H | Recombinant Human C4B Protein, GST-Tagged | Wheat Germ | GST |
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| Human | C4B-1846H | Native Human C4B Protein | Human Plasma | N/A |
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| Human | C4B-3818H | Recombinant Human C4B protein, His-SUMO-tagged | E.coli | His-SUMO | 1454-1744aa |
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| Human | C4B-10H | Native Human C4B Protein | Human serum | N/A |
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| Human | C4B-341H | Recombinant Human C4B Protein, His-tagged | E.coli | N-His | Thr1021-Thr1330 |
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| Human | C4B-343H | Recombinant Human C4B Protein, His-tagged | E.coli | N-His | Leu958-Gly1335 |
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| Human | C4B-08H | Recombinant Human C4B protein, His-tagged | E.coli | His |
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| Human | C4B-340H | Recombinant Human C4B Protein, His-tagged | E.coli | N-His | Gln19-Leu333 |
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| Human | C4B-99H | Native Human C4b Binding Protein | Normal human serum (shown by certified tests to be negative for HBsAg and for antibodies to HCV, HIV-1 and HIV-II) | N/A |
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| Human | C4B-5582H | Recombinant Human C4B protein, His-tagged | Yeast | His | 1454-1744aa |
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| Mouse | C4b-7884M | Recombinant Mouse C4b protein, His & T7-tagged | E.coli | His/T7 | Gln126~Ser366 |
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| Mouse | C4b-0053M | Recombinant Mouse C4b Protein, GST-Tagged | Wheat Germ | GST |
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| Mouse | C4B-2587M | Recombinant Mouse C4B Protein | Mammalian Cell | His |
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| Mouse | C4b-7883M | Recombinant Mouse C4b protein, His & T7-tagged | E.coli | His/T7 | Pro1450~Gln1723 (Accession# P01029) |
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| Mouse | C4b-6785M | Recombinant Mouse C4b protein, His-tagged | E.coli | His | Asn678-Arg753 (Accession # P01029) |
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| Mouse | C4B-1147M | Recombinant Mouse C4B Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | C4B-1147M-B | Recombinant Mouse C4B Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | C4b-342R | Recombinant Rat C4b Protein, His-tagged | E.coli | N-His | Ala1477-Val1737 |
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- C4B Related Articles
C4B involved in several pathways and played different roles in them. We selected most pathways C4B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with C4B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
C4B has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by C4B itself. We selected most functions C4B had, and list some proteins which have the same functions with C4B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
C4B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C4B here. Most of them are supplied by our site. Hope this information will be useful for your research of C4B.
- Q&As
- Reviews
Q&As (6)
Ask a questionC4B inhibitors can be used to treat diseases associated with complement hyperactivation, such as autoimmune diseases and graft-versus-host disease. By inhibiting the activity of C4B, it is possible to attenuate the excessive inflammatory response and tissue damage.
The expression level of C4B is regulated by a variety of factors, including inflammatory factors, cytokines, and drugs. These factors can affect the synthesis and release of C4B, thus affecting its function in the immune system.
It can bind to other complement components and immunoglobulins to form immune complexes. These immune complexes can be recognized and cleared by clearance mechanisms in the body, such as phagocytes.
It is closely related to other immune system components (such as T cells, B cells, antibodies, etc.) and is involved in the immune defense response in the body. The interactions and influences between them are important for maintaining immune homeostasis.
The role of C4B in different types of cells may vary. For example, in immune cells, it can be involved in the regulation of immune responses and cell activation, while in endothelial cells, it may be involved in the process of vascular inflammation and injury.
C4B interacts with other complement components (e.g., C4A, C2, C3, etc.) to form part of the complement activation pathway and is involved in the immune defense response.
Customer Reviews (3)
Write a reviewC4B labeling works very well and can be fluorescently labeled, etc., which is very suitable for our research.
In experiments, biocompatibility showed up very well.
Very good at western-blot experimenting.
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