C9
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Official Full Name
complement component 9
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Overview
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009] -
Synonyms
C9; complement component 9; C9D; ARMD15; complement component C9;
- Recombinant Proteins
- Cell & Tissue Lysates
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Equus caballus (Horse)
- Human
- Mouse
- Mus musculus (Mouse)
- Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
- Oryctolagus cuniculus (Rabbit)
- Rabbit
- Rat
- Rattus norvegicus (Rat)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- Human Plasma
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- His|T7
- N/A
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | C9-26247TH | Recombinant Human C9, GST-tagged | Wheat Germ | His | ||
| Human | C9-5126H | Recombinant Human C9, His-tagged | E.coli | His |
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| Human | C9-7945HCL | Recombinant Human C9 293 Cell Lysate | HEK293 | N/A |
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| Human | C9-58H | Native Human Complement C9 | Human Plasma | N/A |
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| Human | C9-44HF | Recombinant Full Length Human C9 Protein, GST-tagged | In Vitro Cell Free System | GST |
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| Human | C9-0274H | Recombinant Human C9 Protein (Gln22-His265), N-His-tagged | E.coli | N-His | Gln22-His265 |
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| Mouse | C9-1844M | Recombinant Mouse C9 protein, His-tagged | E.coli | His | Pro136~Arg512 |
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| Mouse | C9-2593M | Recombinant Mouse C9 Protein | Mammalian Cell | His |
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| Mouse | C9-05M | Recombinant Mouse C9 Protein | E.coli |
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| Mouse | C9-1149M | Recombinant Mouse C9 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | C9-1149M-B | Recombinant Mouse C9 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | C9-1056R | Recombinant Rat C9 Protein | Mammalian Cell | His |
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| Rat | C9-714R | Recombinant Rat C9 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | C9-714R-B | Recombinant Rat C9 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | C9-349R | Recombinant Rat C9 Protein, His-tagged | E.coli | N-His | Leu336-Arg554 |
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| Rat | C9-04R | Recombinant Rat C9 Protein | E.coli |
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| Rabbit | C9-1845R | Recombinant Rabbit C9 protein, His & T7-tagged | E.coli | His/T7 | Pro139~Lys519 (Accession # P48747) |
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| Bos taurus (Bovine) | RFL3920BF | Recombinant Full Length Bovine Complement Component C9(C9) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (22-548) |
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| Equus caballus (Horse) | RFL28089EF | Recombinant Full Length Horse Complement Component C9(C9) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (22-547) |
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| Mus musculus (Mouse) | RFL27477MF | Recombinant Full Length Mouse Complement Component C9(C9) Protein, His-Tagged | E.coli expression system | His | Full Length (21-548) |
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| Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) | RFL24106OF | Recombinant Full Length Oncorhynchus Mykiss Complement Component C9(C9) Protein, His-Tagged | E.coli expression system | His | Full Length (1-574) |
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| Oryctolagus cuniculus (Rabbit) | RFL34979OF | Recombinant Full Length Rabbit Complement Component C9(C9) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (22-557) |
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| Rattus norvegicus (Rat) | RFL12988RF | Recombinant Full Length Rat Complement Component C9(C9) Protein, His-Tagged | E.coli expression system | His | Full Length (21-554) |
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| Zebrafish | C9-3035Z | Recombinant Zebrafish C9 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- C9 Related Articles
- C9 Related Research Area
C9 involved in several pathways and played different roles in them. We selected most pathways C9 participated on our site, such as Complement and coagulation cascades, Prion diseases, Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with C9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Complement and coagulation cascades | CFI;FGG;A2M;SERPINA1;F2;F11;THBD;KNG1;CFD |
| Prion diseases | IL1B;C1QA;IL6;ELK1;MAPK3;FYN;C5;PRKACG;C9 |
| Amoebiasis | C8A;IFNG;PLCB3;LAMA5;SERPINB1B;CXCL8;ITGB2;PRKCB;ACTN4 |
| Systemic lupus erythematosus | HIST1H2BO;HIST1H4H;HIST1H2AK;HIST2H4A;C8A;HIST1H2AE;HLA-DRB3;SNRPB;HIST1H4D |
C9 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by C9 itself. We selected most functions C9 had, and list some proteins which have the same functions with C9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
C9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C9 here. Most of them are supplied by our site. Hope this information will be useful for your research of C9.
d-mannose
- Q&As
- Reviews
Q&As (7)
Ask a questionC9 mediates inflammation and is key in defense against bacterial infections.
C9 is crucial in forming the MAC, which lyses pathogens and damaged cells in immune defense.
C9 interacts with other complement components to propagate the complement cascade and immune response.
Variations in C9 function or expression can disrupt immune regulation, affecting disease susceptibility and severity.
C9 deficiency increases vulnerability to recurrent bacterial infections due to weakened immune response.
C9 influences ischemic injury outcomes by mediating inflammatory and immune responses.
In autoimmune diseases, C9 can exacerbate symptoms by overactivating the complement system.
Customer Reviews (3)
Write a reviewAccurate protein structural analysis, indispensable for our investigations.
Exceptional protein expression optimization support, highly appreciated.
Reliable mass spectrometry analysis, pivotal for advancing proteomics research.
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