C

  • Official Full Name

    chib
  • Overview

    Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    C;chib;C22orf2, chromosome 22 open reading frame 2 , PGEA1, PKD2 interactor, golgi and endoplasmic reticulum associated 1;protein chibby homolog 1;Cby;Chibby;PIGEA 14;PIGEA14;C22orf2;Cytosolic leucine rich protein;HRIHFB2025;PKD2 interactor, Golgi and endoplasmic reticulum-associated 1;Protein Chibby;OTTHUMP00000198875;OTTHUMP00000198876;OTTHUMP00000198878;ARPP-binding protein;coiled-coil protein PIGEA-14;cytosolic leucine-rich protein;PKD2 interactor, golgi and end;arb1;PGEA1;PIGEA-14;HS508I15A

Recombinant Proteins

  • HBV
  • Rat
  • Streptomyces phage phiC31
  • JEV
  • RuV
  • YEV
  • Mouse
  • Human
  • SARS
  • Measles Virus
  • RUBV
  • DENV
  • HCV
  • HBV-D
  • Hepatitis B virus genotype A2 subtype adw2 (strain Rutter 1979)
  • Hepatitis B virus genotype A2 subtype adw2 (isolate Germany/991/1990)
  • HBV-C
  • Hepatitis B virus genotype C subtype ayr (isolate Human/Japan/Okamoto/-)
  • E.coli
  • Mammalian Cells
  • E.Coli/Yeast
  • P.pastoris
  • HEK293
  • Insect Cells
  • Non
  • His
  • GST
  • SUMO
  • Avi
  • Fc
  • Myc
  • MBP
Cat.# Product name Source (Host) Species Tag Protein Length Price
C -74H Recombinant Hepatitis B Virus C protein E.coli HBV Non 1-149 amino acids
C -75H Recombinant Hepatitis B Virus C protein, His-tagged E.coli HBV His 139 a.a (10-149a.a)
C -76H Recombinant Hepatitis B Virus C protein, His-tagged E.coli HBV His amino acids 1-186
C -77H Recombinant Hepatitis B Virus C protein E.coli HBV Non amino acids 1-144
C -78H Recombinant Hepatitis B Virus C protein, GST-tagged E.coli HBV GST
C-1038R Recombinant Rat C Protein Mammalian Cells Rat His
C-1506S Recombinant Streptomyces phage phiC31 C protein, His-tagged E.Coli/Yeast Streptomyces phage phiC31 His
C-1809J Recombinant JEV C Protein E.coli JEV Non
C-1810R Recombinant RuV (Strain TO-336) C Protein E.coli RuV Non
C-1811Y Recombinant YEV C Protein E.coli YEV Non
C-2556M Recombinant Mouse C Protein Mammalian Cells Mouse His
C-30019TH Recombinant Human C, His-tagged E.coli Human His Full L. 1-126 a.a.
C-313V Recombinant SARS Nucleocapsid core Protein E.coli SARS Non 1-49 a.a.
C-314V Recombinant SARS Nucleocapsid core Protein E.coli SARS Non 340-390 a.a.
C-393V Recombinant Measles Virus Non-Structural C Protein E.coli Measles Virus Non 1-51 a.a.
C-472V Recombinant Rubella Virus Capsid (C) Protein E.coli RUBV Non 1-123 a.a.
C-477V Recombinant SARS Associated Coronavirus Nucleocapsid C Protein E.coli SARS Non
C-485D Recombinant Dengue virus Capsid protein, His-tagged E.coli DENV His 1-100 a.a.
C-733V Recombinant DENV (Strain New Guinea C) C Protein, His-tagged E.coli DENV His 1-100 a.a.
CDE017 Recombinant HBeAg protein, His-tagged E.coli HBV His 10-149 a.a.
HBcAg-19H Recombinant Hepatitis B Virus C protein P.pastoris HBV Non
HCV-01 Recombinant HCV Core protein, His-tagged E.coli HCV His 1-120 a.a.
HCV-02 Recombinant HCV Core protein E.coli HCV Non 2-192 a.a.
C-01H Recombinant HBV (ayr) Core Protein, His-tagged E.coli HBV His 1-149 a.a.
C-02H Recombinant HBV Core Protein E.coli HBV 1-149 a.a.
C-0837H Recombinant HBV C Protein (Met1-Val149), N-His and SUMO tagged E.coli HBV His&SUMO Met1-Val149
C-0839H Recombinant HBV C Protein (Met1-Val149), C-His tagged E.coli HBV His Met1-Val149
C-0840H Recombinant HBV-D ayw (isolate France/Tiollais/1979) C Protein (Met1-Val149), C-His tagged E.coli HBV-D His Met1-Val149
C-1127M Recombinant Mouse C Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
C-1127M-B Recombinant Mouse C Protein Pre-coupled Magnetic Beads HEK293 Mouse
C-2928H Recombinant Hepatitis B virus genotype A2 subtype adw2 C protein, His-tagged E.coli Hepatitis B virus genotype A2 subtype adw2 (strain Rutter 1979) His 1-185aa
C-2929H Recombinant Hepatitis B virus genotype A2 subtype adw2 C protein, His-SUMO-tagged E.coli Hepatitis B virus genotype A2 subtype adw2 (strain Rutter 1979) His&SUMO 1-185aa
C-4532H Recombinant Hepatitis B virus genotype A2 subtype adw2 (isolate Germany/991/1990) C protein, His&Myc-tagged E.coli Hepatitis B virus genotype A2 subtype adw2 (isolate Germany/991/1990) His&Myc 1-185aa
C-654H Recombinant HBV-C (isolate China/Tibet127/2002) C protein(1-183aa) Insect Cells HBV-C Non 1-183aa
C-655H Recombinant HBV-C (isolate China/Tibet127/2002) C protein(1-183aa), His-tagged Insect Cells HBV-C His 1-183aa
C-674H Recombinant Hepatitis B virus genotype C subtype ayr (isolate Human/Japan/Okamoto/-) C protein, MBP&His-Avi-tagged, Biotinylated E.coli Hepatitis B virus genotype C subtype ayr (isolate Human/Japan/Okamoto/-) Avi&His&MBP 20-212a.a.
C-696R Recombinant Rat C Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
C-696R-B Recombinant Rat C Protein Pre-coupled Magnetic Beads HEK293 Rat
C-754V Recombinant HBV-C(isolate Japan/A4/1994) C protein(1-183aa), His-tagged E.coli HBV-C His 1-183aa
CCL20-518H Recombinant Human CCL20 Protein, Fc-tagged HEK293 Human Fc 27-96 a.a.
CD200-06H Active Recombinant Human CD200 Protein, His-tagged Insect Cells Human His 211
CD209-03H Recombinant Human CD209 Protein, hIgG/His-tagged Insect Cells Human Fc&His 587
CD47-08H Active Recombinant Human CD47 Protein, His-tagged Insect Cells Human His 129
HBcAg-001 Recombinant HBcAg Protein, ayr subtype, His-tagged E.coli HBV His 1-149 a.a.

    Involved Pathway

    C involved in several pathways and played different roles in them. We selected most pathways C participated on our site, such as Deactivation of the beta-catenin transactivating complex,Signal Transduction,Signaling by Wnt, which may be useful for your reference. Also, other proteins which involved in the same pathway with C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    TCF dependent signaling in response to WNT BCL9L,CBY1,WNT8-2,LGR6,SOX6,SOX13,PYGO1,WIF1,HECW1B,ZNRF3
    Deactivation of the beta-catenin transactivating complex SOX4B,SOX9B,TLE1,BCL9L,CTBP1,PYGO2,RBBP5,TLE2,SOX32,TLE3B
    Signal Transduction VIP2,NPB,APOM,TNKS2,NF2A,CALML4,RBP4,STRAP,ARHGEF18A,WWOX
    Signaling by Wnt SOX9A,RBBP5,SRY,GPR177,LGR5,BCL9,SOX6,KREMEN1,BCL9L,PRICKLE1B

    Protein Function

    C has several biochemical functions, for example, beta-catenin binding,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C itself. We selected most functions C had, and list some proteins which have the same functions with C. You can find most of the proteins on our site.

    Function Related Protein
    identical protein binding C1QL4,DPY30,CUBN,IAPP,SETX,GBP5,SDF4,RUNX1T1,HNRNPC,COL2A1
    beta-catenin binding MED12L,SMAD7,NF2,SLC9A3R1,PTBP3,VCL,APC,MED12,GRIP1,TCF7L2

    Interacting Protein

    C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C here. Most of them are supplied by our site. Hope this information will be useful for your research of C.

    Hmga2

    Resources

    References

    • Yang, YR; Feng, JD; et al. Immune Responses to a Recombinant Rv0057-Rv1352 Fusion Protein of Mycobacterium tuberculosis. ANNALS OF CLINICAL AND LABORATORY SCIENCE 45:39-48(2015).
    • Khosravi-Farsani, S; Amidi, F; et al. Isolation and Enrichment of Mouse Female Germ Line Stem Cells. CELL JOURNAL 16:406-415(2015).

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