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Official Full Name chib
Background Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms C; chib; C22orf2, chromosome 22 open reading frame 2 , PGEA1, PKD2 interactor, golgi and endoplasmic reticulum associated 1; protein chibby homolog 1; Cby; Chibby; PIGEA 14; PIGEA14; C22orf2; Cytosolic leucine rich protein; HRIHFB2025; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; Protein Chibby; OTTHUMP00000198875; OTTHUMP00000198876; OTTHUMP00000198878; ARPP-binding protein; coiled-coil protein PIGEA-14; cytosolic leucine-rich protein; PKD2 interactor, golgi and end; arb1; PGEA1; PIGEA-14; HS508I15A
    • Species :
    • Dengue
    • DENV
    • HBV
    • HCV
    • Human
    • JEV
    • Measles Virus
    • Mouse
    • Rat
    • Rubella Virus
    • RuV
    • SARS
    • Streptomyces phage phiC31
    • YEV
    • Source :
    • E. coli or Yeast
    • E.coli
    • Mammalian Cell
    • P.pastoris
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human C-30019TH Recombinant Human C, His-tagged E.coli His
    Mouse C-2556M Recombinant Mouse C Protein Mammalian Cell His
    Rat C-1038R Recombinant Rat C Protein Mammalian Cell His
    HBV C -74H Recombinant Hepatitis B Virus C protein E.coli N/A
    HBV C -75H Recombinant Hepatitis B Virus C protein, His-tagged E.coli His
    HBV C -76H Recombinant Hepatitis B Virus C protein, His-tagged E.coli His
    HBV C -77H Recombinant Hepatitis B Virus C protein E.coli N/A
    HBV C -78H Recombinant Hepatitis B Virus C protein, GST-tagged E.coli GST
    Streptomyces phage phiC31 C-1506S Recombinant Streptomyces phage phiC31 C protein, His-tagged E. coli or Yeast His
    JEV C-1809J Recombinant JEV C Protein E.coli N/A
    RuV C-1810R Recombinant RuV (Strain TO-336) C Protein E.coli N/A
    YEV C-1811Y Recombinant YEV C Protein E.coli N/A
    SARS C-313V Recombinant SARS Nucleocapsid core Protein E.coli N/A
    SARS C-314V Recombinant SARS Nucleocapsid core Protein E.coli N/A
    Measles Virus C-393V Recombinant Measles Virus Non-Structural C Protein E.coli N/A
    Rubella Virus C-472V Recombinant Rubella Virus Capsid (C) Protein E.coli N/A
    SARS C-477V Recombinant SARS Associated Coronavirus Nucleocapsid C Protein E.coli N/A
    Dengue C-485D Recombinant Dengue virus Capsid protein, His-tagged E.coli His
    DENV C-733V Recombinant DENV (Strain New Guinea C) C Protein, His-tagged E.coli His
    HBV CDE017 Recombinant HBeAg protein, His-tagged E.coli His
    HBV HBcAg-19H Recombinant Hepatitis B Virus C protein P.pastoris N/A
    HCV HCV-01 Recombinant HCV Core protein, His-tagged E.coli His
    HCV HCV-02 Recombinant HCV Core protein E.coli N/A

    c involved in several pathways and played different roles in them. We selected most pathways c participated on our site, such as Deactivation of the beta-catenin transactivating complex, Signal Transduction, Signaling by Wnt, which may be useful for your reference. Also, other proteins which involved in the same pathway with c were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Deactivation of the beta-catenin transactivating complex CTBP1; BCL9L; TLE3B; SOX9B; C; SRY; SOX6; TLE1; PYGO1; TLE2
    Signal Transduction ARHGAP28; GPR18; IQGAP3; NEDD8L; EVL; GPR31; PNOC; CRABP2; CALML4; CCDC88C
    Signaling by Wnt SOX6; SOX4B; WNT8-2; DACT1; KLHL12; HECW1; BCL9; CSNK1G2; C; SOX9A
    TCF dependent signaling in response to WNT RSPO3; RBBP5; BCL9L; HECW1; SOX9A; LGR4; SRY; TNKS; SOX4A; RSPO1

    c has several biochemical functions, for example, beta-catenin binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by c itself. We selected most functions c had, and list some proteins which have the same functions with c. You can find most of the proteins on our site.

    Function Related Protein
    beta-catenin binding CHD8; RORA; PTBP3; PTPRU; PTPRJ; CDH5; Ar; SOX9; CDH1; CDH2
    identical protein binding NOXO1; KCNJ10; CAV1; DNM1; CRYAB; GRB7; BIRC5; KCNRG; SHANK3; SLK

    c has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with c here. Most of them are supplied by our site. Hope this information will be useful for your research of c.


    Yang, YR; Feng, JD; et al. Immune Responses to a Recombinant Rv0057-Rv1352 Fusion Protein of Mycobacterium tuberculosis. ANNALS OF CLINICAL AND LABORATORY SCIENCE 45:39-48(2015).
    Khosravi-Farsani, S; Amidi, F; et al. Isolation and Enrichment of Mouse Female Germ Line Stem Cells. CELL JOURNAL 16:406-415(2015).

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