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C20orf20

  • Official Full Name

    chromosome 20 open reading frame 20

  • Overview

    Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
  • Synonyms

    C20ORF20; chromosome 20 open reading frame 20; MRG-binding protein; Eaf7; FLJ10914; MRG15BP; MRGBP; MRG(MORF4-related gene)-binding protein; URCC4;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human C20ORF20-26617TH Recombinant Human C20ORF20, His-tagged E.coli His 204 amino acids
Human C20ORF20-26614TH Recombinant Human C20ORF20, His-tagged E.coli His
Human C20orf20-1315H Recombinant Human Chromosome 20 0pen Reading Frame 20, His-tagged E.coli His
Human C20orf20-8119HCL Recombinant Human C20orf20 293 Cell Lysate HEK293 N/A
Human C20orf20-301116H Recombinant Human C20orf20 protein, GST-tagged E.coli GST Met1-Thr204
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • C20orf20 Related Articles
  • C20orf20 Related Research Area

C20orf20 involved in several pathways and played different roles in them. We selected most pathways C20orf20 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with C20orf20 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesING5;ELP4;ANO9A;DNMT3A;YEATS4;GATAD2AB;CAPNS2;SMARCD3;BRPF3
Chromatin organizationKDM5C;BRMS1;KANSL2;PAX3A;MBD3A;MTA2;SUZ12B;YEATS4;SMARCC1B
HATs acetylate histonesPHF17;MSL3;DR1;MSL1A;KANSL2;BRPF3;ACTL6A;KANSL3;KAT7B

C20orf20 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by C20orf20 itself. We selected most functions C20orf20 had, and list some proteins which have the same functions with C20orf20. You can find most of the proteins on our site.

Function Related Protein
protein bindingDCUN1D1;TRAF2;NSMCE1;CD6;SYAP1;STRA13;FLOT1;MRPL11;MORF4L1

C20orf20 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C20orf20 here. Most of them are supplied by our site. Hope this information will be useful for your research of C20orf20.

MORF4L2; MORF4L1; ACTL6A

Ilhan, A; Gartner, W; et al. Localization and characterization of the novel protein encoded by C20orf3. BIOCHEMICAL JOURNAL 414:485-495(2008).
Alvarez, B; Gomez, N; et al. Molecular cloning characterization and expression of porcine immunoreceptor SIRP alpha. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY 31:307-318(2007).
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