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Official Full Name complement component 1, q subcomponent, C chain
Background This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.
Synonyms C1QC; complement component 1, q subcomponent, C chain; C1QG, complement component 1, q subcomponent, gamma polypeptide; complement C1q subcomponent subunit C; complement component 1, q subcomponent, gamma polypeptide; C1QG; C1Q-C; FLJ27103
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • GST
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human C1QC-5655H Recombinant Human C1QC Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human C1QC-8142H Recombinant Human C1QC, MYC/DDK-tagged HEK293 Myc/DDK
    Human C1QC-8142HCL Recombinant Human C1QC 293 Cell Lysate HEK293 N/A
    Human C1QC-926H Recombinant Human C1QC Protein, His-tagged E.coli His
    Human C1QC-927H Recombinant human C1QC protein, His/GST-tagged E.coli His/GST
    Mouse C1QC-2563M Recombinant Mouse C1QC Protein Mammalian Cell His
    Mouse C1qc-731M Recombinant Mouse C1qc Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat C1QC-1044R Recombinant Rat C1QC Protein Mammalian Cell His
    Rhesus Macaque C1QC-586R Recombinant Rhesus monkey C1QC Protein, His-tagged Mammalian Cell His
    Zebrafish C1QC-1502Z Recombinant Zebrafish C1QC Mammalian Cell His

    C1QC involved in several pathways and played different roles in them. We selected most pathways C1QC participated on our site, such as Complement and coagulation cascades, Prion diseases, Pertussis, which may be useful for your reference. Also, other proteins which involved in the same pathway with C1QC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Complement and coagulation cascades A2M; KNG1; MASP2; SERPIND1; C4BPA; C4BP; F9; SERPINE1; C1RA; F2
    Prion diseases LOC100033925; MAPK3; C8A; HSPA1A; C9; BAX; C1QB; FYN; ELK1; C8B
    Pertussis MAPK12; ITGA5; CASP1; NLRP3; ITGB2L; Casp3; ITGB2; TRAF6; TLR4; GM5077
    Chagas disease (American trypanosomiasis) PIK3R2; PPP2R1A; IL10; C3; CALR; PIK3CB; PIK3R3; PPP2R2C; PLCB2; MAPK12
    Staphylococcus aureus infection DSG1C; PTAFR; FGG; HLA-DRA; C1RA; CFB; FCGR3A; DSG1A; HLA-DQA1; HLA-DOA
    Systemic lupus erythematosus C3; C8A; TROVE2; HIST2H2AC; H2AFZ; HLA-DQA2; HIST1H2BP; H2AFB1; HIST1H2AL; HIST1H4J

    C1QC has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by C1QC itself. We selected most functions C1QC had, and list some proteins which have the same functions with C1QC. You can find most of the proteins on our site.

    Function Related Protein

    C1QC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C1QC here. Most of them are supplied by our site. Hope this information will be useful for your research of C1QC.


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