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C1QC

  • Official Full Name

    complement component 1, q subcomponent, C chain

  • Overview

    This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.
  • Synonyms

    C1QC; complement component 1, q subcomponent, C chain; C1QG, complement component 1, q subcomponent, gamma polypeptide; complement C1q subcomponent subunit C; complement component 1, q subcomponent, gamma polypeptide; C1QG; C1Q-C; FLJ27103;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mamanlian cells
  • Mammalian Cell
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human C1QC-926H Recombinant Human C1QC Protein, His-tagged E.coli His
Human C1QC-8142H Recombinant Human C1QC, MYC/DDK-tagged HEK293 Myc/DDK
Human C1QC-8142HCL Recombinant Human C1QC 293 Cell Lysate HEK293 N/A
Human C1QC-5655H Recombinant Human C1QC Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human C1QC-927H Recombinant human C1QC protein, His/GST-tagged E.coli His/GST 129
Human C1QC-1279HFL Recombinant Full Length Human C1QC, Flag-tagged Mamanlian cells Flag
Human C1QC-334H Recombinant Human C1QC Protein, His-tagged E.coli N-His Lys117-Asp245
Human C1QC-0480H Recombinant Human C1QC Protein (Lys115-Asp245), N-His-tagged E.coli N-His Lys115-Asp245
Human C1QC-335H Recombinant Human C1QC Protein, His&GST-tagged E.coli N-His&GST Lys117-Asp245
Mouse C1QC-2563M Recombinant Mouse C1QC Protein Mammalian Cell His
Mouse C1QC-1133M Recombinant Mouse C1QC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse C1qc-731M Recombinant Mouse C1qc Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse C1QC-1133M-B Recombinant Mouse C1QC Protein Pre-coupled Magnetic Beads HEK293
Rat C1QC-1044R Recombinant Rat C1QC Protein Mammalian Cell His
Rat C1qc-336R Recombinant Rat C1qc Protein, His-tagged E.coli N-His Lys115-Asp245
Rat C1QC-702R-B Recombinant Rat C1QC Protein Pre-coupled Magnetic Beads HEK293
Rat C1QC-702R Recombinant Rat C1QC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque C1QC-586R Recombinant Rhesus monkey C1QC Protein, His-tagged Mammalian Cell His
Rhesus Macaque C1QC-414R Recombinant Rhesus Macaque C1QC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque C1QC-414R-B Recombinant Rhesus Macaque C1QC Protein Pre-coupled Magnetic Beads HEK293
Zebrafish C1QC-1502Z Recombinant Zebrafish C1QC Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • C1QC Related Research Area

C1QC involved in several pathways and played different roles in them. We selected most pathways C1QC participated on our site, such as Complement and coagulation cascades, Prion diseases, Pertussis, which may be useful for your reference. Also, other proteins which involved in the same pathway with C1QC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Complement and coagulation cascadesGM5077;FGA;F9;F13A1;LOC100514666;C4BP;FGG;MASP1;CR1
Prion diseasesCCL5;C8B;C6;PRNP;SOD1;NCAM2;LAMC1;PRKACG;LOC100033925
PertussisCALM4;GNAI2;C4BPB;C3;TNF;Il23a; Il12b;C1S;TLR4;C4BP
Chagas disease (American trypanosomiasis)TGFB3;IFNGR1;PPP2R1B;PIK3R2;C1QC;PLCB1;SMAD3;MAPK9;GNAO1
Staphylococcus aureus infectionPLG;C5;FCGR1A;FCGR3;DSG1;FCGR4;FPR3;H2-AA;C4A
Systemic lupus erythematosusACTN4;HIST1H3C;C2;HIST1H2BQ;GM14478;HIST1H2BK;HIST2H2AA2;CD28;H2AFB3

C1QC has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by C1QC itself. We selected most functions C1QC had, and list some proteins which have the same functions with C1QC. You can find most of the proteins on our site.

Function Related Protein

C1QC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with C1QC here. Most of them are supplied by our site. Hope this information will be useful for your research of C1QC.

C1QA; TFAP2A; APOA1

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