|Official Full Name||complement component 6|
|Background||This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]|
|Synonyms||C6; complement component 6; complement component C6;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
c6 involved in several pathways and played different roles in them. We selected most pathways c6 participated on our site, such as Complement and coagulation cascades, Prion diseases, Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with c6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Complement and coagulation cascades||SERPINA5; CFH; C1S; A2M; SERPINE1; CD59A; Hc; C1QC; F8; C1R|
|Prion diseases||MAP2K1; C1QB; LOC100033925; ELK1; IL6; C8A; LAMC1; Hc; IL1B; CASP12|
|Systemic lupus erythematosus||HIST1H2BF; HIST1H2BH; HIST2H4; ELANE; HIST1H2BM; C7; HLA-DMB; HIST1H2AO; FCGR1; HLA-DRB5|
c6 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by c6 itself. We selected most functions c6 had, and list some proteins which have the same functions with c6. You can find most of the proteins on our site.
|protein binding||PLEKHM1; AJUBA; TBKBP1; MYL6; NCOR2; FRMD6; TNFRSF11A; NEFM; PDK1; HACE1|
c6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with c6 here. Most of them are supplied by our site. Hope this information will be useful for your research of c6.
ABL1; FYN; NCK1; GRB2; SART3; d-mannose